Patterns of Neural Connectivity Seen As Key to Intelligence

New brain imaging research explores neurobiological reasons for individual differences in intelligence.

In the study, researchers from Goethe University Frankfurt combined brain scans from over 300 persons with modern network analysis methods to better understand differences in cognitive abilities and resulting differences in academic success and professional careers.

As published in the journal Scientific Reports, investigators found that intelligent people have brain regions that interact closely while others appear to have an uncoupling of certain areas of the brain.

Ph.D. student Kirsten Hilger with Drs. Christian Fiebach and Ulrike Basten from the Department of Psychology explain these differences go hand in hand with differences in the patterns of integration among functional modules of the brain.

The research builds upon a prior study that identified brain regions, among them the prefrontal cortex, which when activated are reliably associated with individual differences in intelligence. Until recently, however, it was not possible to examine how such “intelligence regions” in the human brain are functionally interconnected.

Earlier this year, the research team reported that in more intelligent persons two brain regions involved in the cognitive processing of task-relevant information (i.e., the anterior insula and the anterior cingulate cortex) are connected more efficiently to the rest of the brain.

Another brain region, the junction area between temporal and parietal cortex that has been related to the shielding of thoughts against irrelevant information, is less strongly connected to the rest of the brain network.

“The different topological embedding of these regions into the brain network could make it easier for smarter persons to differentiate between important and irrelevant information, which would be advantageous for many cognitive challenges,” said Basten, the study’s principal investigator.

In the new research, investigators explored the hypothesis that the brain is functionally organized into modules.

“This is similar to a social network which consists of multiple sub-networks (e.g., families or circles of friends). Within these sub-networks or modules, the members of one family are more strongly interconnected than they are with people from other families or circles of friends.

”Our brain is functionally organized in a very similar way: There are sub-networks of brain regions — modules — that are more strongly interconnected among themselves while they have weaker connections to brain regions from other modules.”

Investigators examined whether the role of specific brain regions for communication within and among brain modules varies with individual differences in intelligence. That is, whether a specific brain region supports the information exchange within their own ”family” more than information exchange with other ”families,” and how this relates to individual differences in intelligence.

The study shows that in more intelligent persons certain brain regions are clearly more strongly involved in the exchange of information between different sub-networks of the brain in order for important information to be communicated quickly and efficiently.

On the other hand, the research team also identified brain regions that are more strongly de-coupled from the rest of the network in more intelligent people. This may result in better protection against distracting and irrelevant inputs.

“We assume that network properties we have found in more intelligent persons help us to focus mentally and to ignore or suppress irrelevant, potentially distracting inputs,” Basten said.

The reason behind these links remain an open question at present. “It is possible that due to their biological predispositions, some individuals develop brain networks that favor intelligent behaviors or more challenging cognitive tasks.

“However, it is equally as likely that the frequent use of the brain for cognitively challenging tasks may positively influence the development of brain networks. Given what we currently know about intelligence, an interplay of both processes seems most likely.”

Source: University of Frankfurt