Researchers from the University of Seville have patented a pain relief approach that uses nanotechnology to deliver a cannabinoids-based formula to relieve chronic neuropathic pain.
Investigators say a scheduled release of the cannabinoid provided neuropathic pain relief in rats for a period of eleven days after the oral administration of a single dose.
Cannabinoids are classes of chemical compounds that act on specific brain receptors in cells that alter neurotransmitter release; they can be produced naturally in the body, derived from cannabis and other plants or manufactured synthetically.
The innovative approach is based on using polymer nanoparticles to deliver active ingredients.¬†Nanotechnology is used to encapsulate the main active ingredients in a polymer matrix composite. In this way, it is possible to extend the therapeutic effect while reducing the necessary dosage.
In addition, the active ingredients cannot cross the blood-brain barrier, which removes any potential psychoactive effect.
Researchers believe the new technology will be a very important advance in the treatment of chronic pain.
The research appears in Nanomedicine: Nanotechnology, Biology, and Medicine.