New research finds that exercise can delay declines in mobility and help to maintain quality of life for individuals with Parkinson’s disease.
Parkinson’s disease (PD) is a progressive condition that often results in mobility impairments and can lead to decreased health-related quality of life (HRQL) and death.
In the new study, researchers determined that people who exercised regularly had significantly slower declines in HRQL and mobility over a two-year period. Importantly, investigators determined that exercise can provide a significant benefit to those with advanced PD.
The research appears in the Journal of Parkinson’s Disease.
Lead investigator Miriam R. Rafferty, Ph.D., of Northwestern University and Rehabilitation Institute of Chicago, describes the main findings of the study.
“We found that people with Parkinson’s disease who maintained exercise 150 minutes per week had a smaller decline in quality of life and mobility over two years compared to people who did not exercise or exercised less.
The smaller decline was significant for people who started the study as regular exercisers, as well as for people who started to exercise 150 minutes per week after their first study-related visit.”
The data came from the National Parkinson Foundation Quality Improvement Initiative (NPF-QII), an international, multicenter, prospective clinical study of care and outcomes. Over 3400 participants provided data over two years, with information collected during at least three clinic visits.
The NPF-QII study collects a variety of data on pharmacologic and non-pharmacologic management of PD symptoms. These observational study visits are scheduled on a yearly basis. At each visit, exercise is measured by the self-reported number of hours per week of exercise.
Although this study did not determine which type of exercise is best, it suggests that any type of exercise done with a “dose” of at least 150 minutes per week is better than not exercising.
“People with PD should feel empowered to find the type of exercise they enjoy, even those with more advanced symptoms,” remarked Dr. Rafferty.
An unanticipated finding from the study was that the HRQL benefit associated with 30-minute increases in exercise per week was greatest in people with advanced PD.
This finding suggests the value of making exercise and physical activity more accessible to people with more severe disability.
The distinction is important as people with more advanced PD may have poor access to regular exercise, as their mobility impairments would limit their independent participation in existing community and group exercise programs.
“The most important part of the study,” according to Dr. Rafferty, “is that it suggests that people who are not currently achieving recommended levels of exercise could start to exercise today to lessen the declines in quality of life and mobility that can occur with this progressive disease.”
Source: IOS Press/EurekAlert