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Liver Disorders Increase Risk of Depression and Anxiety in Young Adults

Liver Disorders Increase Risk of Depression and Anxiety in Young Adults

Emerging research finds that many teens and young adults with chronic liver conditions suffer from depression and anxiety. The mental health disorders can have considerable impacts on their emotional and physical health, say investigators.

The findings, which appear in Liver Transplantation, indicate that greater attention should be directed to the mental health of these young patients.

Adolescence is a challenging time for young people in general, but even more so for those with medical conditions. Young people with chronic illness have higher rates of mental health problems than the general population, which can affect how well they take care of themselves.

In the new study, a team led by Marianne Samyn, M.D., FRCPCH and Anna Hames, of King’s College Hospital investigated the prevalence of anxiety and depression in young people with chronic liver diseases.

The researchers also sought to identify the factors that might cause distress in these young patients and how anxiety and depression might affect their beliefs about their illness and treatment.

For the study, 187 patients aged 16 to 25 years who were attending an outpatient liver transition clinic in London completed an electronically-administered questionnaire. The clinic is a multidisciplinary service dedicated to young patients with a range of liver conditions that aims to provide developmentally appropriate care and a smooth transition between pediatric and adult services.

Patients were divided in three groups: those who had undergone liver transplantation, those with autoimmune liver disease, and those with other chronic liver conditions.

Based on the questionnaire, 17.7 percent of the patients in the study screened positive for anxiety or depression, which is significantly higher than the four percent to six percent prevalence in the general adolescent population. There were no significant differences between disease groups.

Patients most frequently attributed their distress to fatigue, sleep difficulties, financial concerns, problems at work/school, worry, and low self-esteem.

Depression and anxiety seemed to influence how patients felt their illness affected them emotionally, how concerned they were about their illness, how many symptoms they experienced, and how much impact they felt the illness had on their lives.

Depression and anxiety did not have a significant relationship with patients’ perceived understanding of their illness or their beliefs as to how much treatment can help.

“Health care professionals should be aware of the high prevalence of mental health problems in young people with liver conditions and routinely inquire about young people’s psychosocial circumstances as both can impact on their illness and outcome,” said Dr. Samyn.

“Interestingly, the most common concerns young people with liver conditions report — such as lethargy, problems with sleeping and money, and work- or school-related issues — are very similar to their peers and can be addressed by a multidisciplinary team looking after them.”

Source: Wiley/EurekAlert

Liver Disorders Increase Risk of Depression and Anxiety in Young Adults

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Liver Disorders Increase Risk of Depression and Anxiety in Young Adults. Psych Central. Retrieved on November 29, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 28 Oct 2016)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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