A new imaging study has mapped various emotional states as they flicker across the human brain.
“It’s getting to be a bit like mind-reading,” said Dr. Kevin LaBar, a professor of psychology and neuroscience at Duke University. “Earlier studies have shown that functional MRI can identify whether a person is thinking about a face or a house. Our study is the first to show that specific emotions like fear and anger can be decoded from these scans as well.”
While the data produced by a functional MRI hasn’t changed, the Duke researchers say they are applying new multivariate statistics to the scans of brain activity to see different emotions as networks of activity distributed across areas of the conscious and unconscious brain.
These networks were first mapped by the researchers in a March 2015 paper in the journal Social, Cognitive and Affective Neuroscience. They identified seven different patterns of brain activity reflecting contentment, amusement, surprise, fear, anger, sadness, and neutrality.
To build these maps, they put 32 research subjects into the scanner and exposed them to two music clips and two film clips that had been shown to induce each of the seven emotions. The subjects also completed questionnaires on their moods for further validation.
Analytical software called a machine-learning algorithm was then presented with some of the subjects’ data and tasked with finding a pattern that concurred with each emotional stimulus. Having learned what each of the seven states ought to look like, the algorithm was then presented with the scans of the rest of the study group and asked to identify their emotional states without knowing which emotion prompt they received, the researchers explained.
According to LaBar, the model performed better than chance at this task, despite differences in brain shapes and arousal levels between subjects. “And it proved fairly sensitive,” he said.
The latest study, published in Plos Biology, followed up by scanning 21 subjects who were not offered stimuli, but were encouraged to let their minds wander. Every 30 seconds, they responded to a questionnaire about their current emotional state.
“We tested whether these seven brain maps of emotions occurred spontaneously while participants were resting in the fMRI scanner without any emotional stimuli being presented,” LaBar said.
Data for the whole brain was collected every two seconds and each of these individual scans was compared to the seven patterns. The researchers examined the scanner data for the 10 seconds before each self-report of mood, and found that the algorithm accurately predicted the moods the subjects self-reported.
LaBar said another source of validation is the indication that there’s a significant signal of anxiety at the beginning of each subjects’ data as they enter the confined, noisy MRI for the first time.
“That’s what you’d expect to see for most people when they first enter the machine,” he said.
In a second group of 499 subjects scanned for the Duke Neurogenetics Study, the researchers had them rest in the scanner for nearly nine minutes, and then asked them how depressed and anxious they felt after the scanning session.
“We found that the cumulative presence of our ‘sad’ emotion map, summed over time, predicted their depression scores, and the cumulative presence of our ‘fear’ emotion map predicted their anxiety scores,” LaBar said.
This larger group was also tested for personality measures of depression, anxiety, and angry hostility. Again, the maps for depression and anxiety closely mirrored these measures, the study found.
“We also showed that the cumulative presence of our ‘angry’ emotion map predicted individuals’ angry hostility traits,” LaBar said.
Aside from being an interesting proof of concept, LaBar thinks these new maps of emotional states could be useful in studying people who have poor insight into their emotional status, and might be used in clinical trials to test the effectiveness of treatments to regulate emotions.
Source: Duke University
PHOTO: A Duke team has mapped the distinct patterns of brain activity that correspond to seven different emotional states. The brain anatomy presented here is an average of data from 32 study subjects. Credit: Philip Kragel, Kevin LaBar, Duke University.