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Pre-Stroke Cardiac Risk Ups Risk of More Strokes, Dementia

Pre-Stroke Cardiac Risk Ups Risk of More Strokes, Dementia

First-stroke survivors who were previously diagnosed with high blood pressure, diabetes, and/or other heart disease risk factors may be at greater risk of having subsequent strokes or developing dementia during the following five years, according to a new study published in the American Heart Association’s journal Stroke.

“We already know that stroke patients have an increased risk of recurrent stroke and dementia. What we didn’t know was whether this increased risk persists for a long time after stroke and whether heart disease risk factors present before the first stroke influenced the risk of recurrent strokes or dementia,” said M. Arfan Ikram, M.D., Ph.D., senior study author.

“Our study found these risk factors influence future stroke and dementia and the risks persist for an extended period in some patients.”

Researchers evaluated a group of 1,237 stroke survivors from an existing long-term study and compared them to a stroke-free group of about 5,000 people from the same study.

Their findings showed that one year after suffering a stroke, survivors retain a high risk of a recurrent stroke or dementia for at least five years. After one year, first-time stroke survivors were three times more likely than those who hadn’t suffered a stroke to have a recurrent stroke. Furthermore, stroke survivors were nearly two times more likely to have dementia than those who had not suffered stroke.

Among the stroke survivors, 39 percent of recurrent strokes and 10 percent of post-stroke dementia cases were attributed to pre-stroke cardiovascular risk factors, such as high blood pressure; diabetes; low levels of high-density lipoprotein (HDL, the good cholesterol); smoking; and transient ischemic attack (TIA, or mini-stroke).

“This study suggests that risk factors that lead to the initial stroke may also predispose patients to worsening mental and physical health after stroke. This also applies to risk of death after stroke. We found in a previous study that 27 percent of all deaths after stroke can be attributed to risk factors already present before stroke,” said Ikra, an associate professor in the department of epidemiology, neurology and radiology, Erasmus University Medical Center in Rotterdam, the Netherlands.

Closely monitoring and caring for cardiovascular risk factors — even if you have never experienced a stroke — is not only important to prevent a first stroke, but it can go a long way to prevent a second stroke and dementia, he added.

Stroke is the fifth most common cause of death and a leading cause of disability in the United States.

Source: American Heart Association


Pre-Stroke Cardiac Risk Ups Risk of More Strokes, Dementia

Traci Pedersen

Traci Pedersen is a professional writer with over a decade of experience. Her work consists of writing for both print and online publishers in a variety of genres including science chapter books, college and career articles, and elementary school curriculum.

APA Reference
Pedersen, T. (2018). Pre-Stroke Cardiac Risk Ups Risk of More Strokes, Dementia. Psych Central. Retrieved on November 29, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 16 Jul 2016)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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