Young children living in economically disadvantaged areas are at greater risk of medication poisoning that will require medical attention and intervention, according to a new study from the University of Pittsburgh and the University of California, San Diego.
For the study, researchers analyzed data from the Pittsburgh Poison Center to gain insight into potential geographic targets for poison prevention outreach. They found that the highest risk areas tend to be rural with high rates of unemployment, along with lower rates of high school graduation and lower household income.
“More study is needed to determine exactly why this is, but we believe it could be related to fewer resources for child supervision — whether at home or at daycare centers in the community — increasing the likelihood of a small child finding and swallowing medication,” said senior author Anthony Fabio, Ph.D., M.P.H., assistant professor of epidemiology at Pitt Public Health.
“Understanding where there are geographic clusters of kids being exposed to medications that could hurt them gives us the opportunity to effectively intervene,” said Fabio. “It also could help emergency clinicians to ask the right questions and perhaps zero in on a medication exposure when a child comes in with unexplained symptoms.”
The researchers looked at 26,685 Pittsburgh Poison Center records of pharmaceutical drug exposures — typically defined as ingesting a medication — in children under 5 years old from 2006 through 2010.
They categorized the exposures based on whether there was simply a call to the center and advice given for treatment at home, or if the center staff felt the exposure warranted medical evaluation and referred the child to a nearby health care facility.
By mapping the exposures in this way, the researchers revealed distinct “exposure” and “referral” locations, or geographic clusters, throughout western and central Pennsylvania. The exposure clusters generally included urban areas where people are perhaps more familiar with the Pittsburgh Poison Center’s hotline and, therefore, more likely to call.
The referral clusters are generally in more rural areas characterized by high unemployment. The researchers found that in these areas, the likelihood of a child under 5 being referred to a health care facility for a medication exposure is 3.2 times greater than other areas.
“These results have become a real eye-opener for us,” said co-author Anthony F. Pizon, M.D., an associate professor of emergency medicine at Pitt.
“We now recognize the population of children most vulnerable to potentially harmful medication exposure. Our hope is that we can better tend to the needs of these children through Poison Center outreach efforts and more effectively prevent childhood poisonings.”
The findings are published in the journal Clinical Toxicology.