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Long-term Opioid Therapy Not Effective for Most Women

Long-term Opioid Therapy Less Effective for Many Women

A new study shows that women — especially younger women — are less likely than men to find relief from pain with long-term opioid use.

The new study, published in the Journal of Women’s Health, found that only one in five women reported low levels of pain and high levels of function with chronic opioid therapy.

In the study, researchers led by Linda LeResche, Sc.D., of the Department of Oral Medicine at the University of Washington School of Dentistry in Seattle, evaluated pain status among chronic opioid therapy users.

The researchers report that young and middle-aged women are at particularly high risk for unfavorable global pain status.

Additionally, young and middle-aged women face “unique risks” from opioid use, such as reduced fertility and potential effects of opioids used during pregnancy on the developing fetus, the researchers reported.

“Given the high rates of chronic opioid use in women, along with evidence of poor relief from pain and concerning risks, particularly in reproductive-aged women, we need more effective and safer options for managing pain in this population,” noted Susan G. Kornstein, M.D., editor-in-chief of the Journal of Women’s Health, executive director of the Virginia Commonwealth University Institute for Women’s Health in Richmond, Virginia, and president of the Academy of Women’s Health.

Source: Journal of Women’s Health

Long-term Opioid Therapy Less Effective for Many Women

Janice Wood

Janice Wood is a long-time writer and editor who began working at a daily newspaper before graduating from college. She has worked at a variety of newspapers, magazines and websites, covering everything from aviation to finance to healthcare.

APA Reference
Wood, J. (2018). Long-term Opioid Therapy Less Effective for Many Women. Psych Central. Retrieved on December 3, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 10 Oct 2015)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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