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Effective Smoking Cessation Drug Safe to Use

Effective Smoking Cessation Drug Safe to Use

New research from Europe has determined a beneficial drug that helps smokers to quit does not increase their risk of heart attack and depression, as some earlier research had suggested.

Researchers from the Universities of Edinburgh and Dusseldorf say doctors can prescribe varenicline — also known as Champix™ or ChantixTM — more widely to help people stop smoking.

Varenicline is the most effective medication to help smokers quit but previous reports have suggested that users may be more likely to suffer a heart attack.

The drug has also been linked to depression, self-harm, and suicide.

This latest research, which has for the first time simultaneously studied these potential side effects, supports recent studies that failed to find any evidence that varenicline has a negative effect on mental health. It also shows that taking the drug does not raise a person’s risk of heart disease.

The team looked at anonymised health information from more than 150,000 smokers across England.

The patients had been prescribed either varenicline or another anti-smoking drug called bupropion to help them quit, or had used nicotine replacement therapy — such as patches, chewing gum, or lozenges.

They were tracked for six months to assess any impact of the treatment on their health.

Researchers found that people taking either varenicline or buproprion were no more likely to suffer a heart attack than those using nicotine replacement therapy.

People were also not at higher risk of depression or self-harm, researchers say.

The study appears in the journal The Lancet Respiratory Medicine.

Daniel Kotz, Ph.D., from the Medical Faculty of the Heinrich-Heine-University Dusseldorf, said, “Smokers typically lose three months of life expectancy for every year of continued smoking. Our research supports the use of varenicline as an effective and safe tool to help people quit.”

Aziz Sheikh, M.D., M.Sc., co-director of the University of Edinburgh’s Centre for Medical Informatics, said, “On the basis of our extensive analysis, we believe it is highly unlikely that varenicline has any significant adverse effects on cardiac or mental health.

“Regulators such as the United States Food and Drug Administration (FDA) should review its safety warning in relation to varenicline as this may be unnecessarily limiting access to this effective smoking cessation aid.”

Source: University of Edinburgh/EurekAlert

Effective Smoking Cessation Drug Safe to Use

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Effective Smoking Cessation Drug Safe to Use. Psych Central. Retrieved on September 29, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 8 Sep 2015)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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