Home » News » Football Brain Injuries Require More Study
Football Brain Injuries Require More Study

Football Brain Injuries Require More Study

The claim that playing football can result in lifelong damage to the brain may be premature.

Reports have routinely linked aggression, violence, depression, and suicide with chronic traumatic encephalopathy (CTE), a neurodegenerative brain disease linked to playing football.

But just how CTE and behavioral changes are related is an extremely complex and, as yet, poorly understood issue, write University at Buffalo (UB) researchers in a new research paper.

The paper traces the reporting of neuropsychiatric symptoms now associated with CTE back to a 1928 publication in the Journal of the American Medical Association titled “Punch Drunk.”

The new paper is published in the Journal of Neuropsychiatry and Clinical Neurosciences.

That publication chronicled behavioral problems in individuals, presenting as “cuckoo, goofy, or slug nutty,” following one or more blows to the head. In the historic research, investigators discussed the similarity of these symptoms to other brain disorders that involved encephalitis, inflammation of the brain.

Since then, the UB researchers write, discussion of these symptoms has evolved as new technologies have helped identify specific brain changes that occur after blows to the head result in forces being transferred to the brain.

The UB researchers conclude that long-term or longitudinal research of the effects of CTE has not been performed.

Further the absence of “research-accepted diagnostic criteria for identifying individuals who are considered at risk for CTE” are a hindrance to establishing and understanding the causal relationship between CTE and behavioral health symptoms.

“According to the research community, there is a need for more empirical evidence,” said Daniel Antonius, Ph.D., lead author and assistant professor in the UB Department of Psychiatry in the School of Medicine and Biomedical Sciences.

“In order for a causal relationship between CTE and behavioral changes to be established, this phenomenon needs to be systematically studied in a large sample of contact and non-contact sports athletes over a long period of time, ideally starting early in their careers.”

So far, Antonius notes, peer-reviewed literature on CTE consists primarily of case review studies about specific individuals and post-mortem research.

“We did a thorough review of the literature and what stood out is that case studies predominate,” he said. “Case studies are illuminating and important but they cannot be used to properly establish clinical criteria for diagnosing a medical or psychiatric condition.”

Research that led to this publication was partially supported by grants from the National Football League Charities, the Buffalo Sabres Foundation, the Robert Rich Family Foundation, the Ralph Wilson Foundation, and the Program for Understanding Childhood Concussion and Stroke.

In order to better understand CTE and behavioral symptoms, it also is necessary to develop an appropriate animal model. But Antonius said current animal models for traumatic brain injury (TBI), with which CTE has significant overlap, provides insight into the difficulties of developing such a model.

“Trying to develop an animal model is an important starting point,” he said, “but with TBI, for example, people have had animal models they’ve been studying for decades and they still do not have a perfect model.

“Like CTE, traumatic brain injury involves so many factors, including brain deficits and abnormalities affecting different areas of the brain, as well as various behavioral manifestations. Coming up with an animal model will be difficult and take years.”

The authors of the paper are involved in a multidisciplinary research and treatment study at UB called the Healthy Aging Mind Project, organized last year, to help former professional athletes maintain quality of life while also studying how they age.

“We wanted to work with former professional football and hockey players, and other athletes, to see what happens to their minds and brains, and mental health, as they age while helping them and their families identify treatment and counseling opportunities,” said Antonius.

Source: University of Buffalo


Brain football photo by shutterstock.

Football Brain Injuries Require More Study

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Football Brain Injuries Require More Study. Psych Central. Retrieved on September 25, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 8 Dec 2014)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
Published on Psych All rights reserved.