Meditation, Support Groups Shown to Impact Cell Biology in Cancer Survivors

Canadian researchers say they have proof that practicing mindfulness meditation or being involved in a support group has a positive physical impact at the cellular level in breast cancer survivors.

Investigators from the Alberta Health Services’ Tom Baker Cancer Centre discovered that telomeres — protein complexes at the end of chromosomes — maintain their length in breast cancer survivors who practice meditation or are involved in support groups.

The finding is in contrast to what was demonstrated in a comparison group (without intervention) where the telomeres shortened.

Although the disease-regulating properties of telomeres aren’t fully understood, shortened telomeres are associated with several disease states, as well as cell aging. Longer telomeres are thought to be protective against disease.

“We already know that psychosocial interventions like mindfulness meditation will help you feel better mentally, but now for the first time we have evidence that they can also influence key aspects of your biology,” says Dr. Linda E. Carlson, Ph.D., principal investigator and director of research.

“It was surprising that we could see any difference in telomere length at all over the three-month period studied,” Carlson said.

“Further research is needed to better quantify these potential health benefits, but this is an exciting discovery that provides encouraging news.”

The study has been published online in the journal Cancer.

Investigators followed a total of 88 breast cancer survivors who had completed their treatments for at least three months. The average age was 55 and most participants had ended treatment two years prior. To be eligible, they also had to be experiencing significant levels of emotional distress.

In the Mindfulness-Based Cancer Recovery group, participants attended eight weekly, 90-minute group sessions that provided instruction on mindfulness meditation and gentle hatha yoga, with the goal of cultivating non-judgmental awareness of the present moment. Participants were also asked to practice meditation and yoga at home for 45 minutes daily.

In the Supportive Expressive Therapy group, participants met for 90 minutes weekly for 12 weeks and were encouraged to talk openly about their concerns and their feelings. The objectives were to build mutual support and to guide women in expressing a wide range of both difficult and positive emotions, rather than suppressing or repressing them.

Control group participants were randomly selected and attended one, six-hour stress management seminar.

All study participants had their blood analyzed and telomere length measured before and after the interventions.

While scientists have shown the interventions provide a short-term effect on telomere length compared to a control group, it’s not known if the effects are lasting.

Future research will address this gap as studies are planned to see if the psychosocial interventions have a positive impact beyond the three months studied.

Allison McPherson was first diagnosed with breast cancer in 2008. When she joined the study, she was placed in the mindfulness-based cancer recovery group.

Today, she says that experience has been life-changing.

“I was skeptical at first and thought it was a bunch of hocus-pocus,” said McPherson, who underwent a full year of chemotherapy and numerous surgeries.

“But I now practice mindfulness throughout the day and it’s reminded me to become less reactive and kinder toward myself and others.”

Study participant Deanne David was also placed in the mindfulness group.

“Being part of this made a huge difference to me,” she says. “I think people involved in their own cancer journey would benefit from learning more about mindfulness and connecting with others who are going through the same things.”

Source: Alberta Health Services/EurekAlert