The study, which compares two different family-based therapies, adds to a growing body of evidence supporting the value of parents’ involvement in anorexia treatment, according to researchers at Stanford University.
“The take-away message for parents is that, first, there is good treatment available for their child who is struggling with anorexia,” said Stewart Agras, M.D., professor emeritus of psychiatry and behavioral sciences at Stanford and the lead author of the new study. “Second, the preferred treatment is family-based therapy in which parents help their child regain weight.”
Anorexia nervosa patients suffer distorted body image, believing they are overweight. They overexercise and refuse to eat enough to maintain a healthy body weight. The disease, which affects about 0.5 to 0.7 percent of adolescent girls, has one of the highest suicide rates of any psychiatric disorder, according to the researchers.
“For a long time, people blamed families for causing anorexia and thought they should be left out of treatment,” said James Lock, M.D., Ph.D., professor of psychiatry and behavioral sciences at Stanford and a co-author of the study. “But this study suggests that, however you involve them, families can be useful, and that more focused family treatment works faster and more cost-effectively for most patients.”
The study, a randomized, controlled trial of 164 patients conducted at six sites in the United States and Canada, compared two forms of anorexia treatment that involved regular therapy sessions with adolescents and their families.
One approach focused on teaching parents to help their children eat normally and regain weight at home. The other attempted to resolve difficult family dynamics.
Both therapies produced similar rates of recovery from anorexia, but patients treated with the first approach gained weight faster and needed less hospitalization, the study found.
The patients were ages 12-18 and had been ill with anorexia for an average of 13.5 months. At the start of the study, all had body weights of at least 75 percent of what was considered ideal, meaning that physicians considered it safe for them to receive outpatient treatment.
Nearly 90 percent of the patients were female. All had at least one parent who agreed to participate in treatment, which consisted of 16 one-hour therapy sessions over a nine-month period.
The success of the treatments was evaluated at the end of the nine-month period and again a year later, according to the researchers.
The therapy that focused on teaching parents to help their children eat normally again was about half as expensive as the family-dynamics approach, mostly because patients spent less time in the hospital, researchers explained.
However, the therapy that focused on family dynamics was more effective for one specific sub-group of patients: those who also had severe symptoms of obsessive-compulsive disorder, the study found.
Lock, who has done several previous studies of the therapy that teaches parents to help their children eat normally again, said he thinks this approach works by interrupting the patient’s behaviors that support erroneous thinking patterns.
“We think that parents are able to disrupt the maintaining behaviors of anorexia long enough that the thoughts and cognitions that go with the disease diminish,” he said. “At that point, the cognitions themselves have very little staying power.”
Tackling anorexia during the teenage years offers the best hope for long-term remission, Agras said.
“The longer anorexia goes on, the more difficult it is to treat,” he said. “A great many people live chronically restricted lives because of this disease — they plan their days around undereating and overexercise — and quite a few die. The idea is to treat the disorder in adolescence to prevent more adults from becoming anorexic.”
The study was published in JAMA Psychiatry.