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Pilot Program Finds Early Autism Intervention Beneficial

Pilot Program Finds Early Autism Intervention Beneficial

Provocative new research suggests treatment for autism during infancy can significantly reduce symptoms so that by age three, most who received the therapy had neither autistic spectrum disorder (ASD) nor developmental delay.

Researchers from the University of California, Davis MIND Institute developed the therapeutic program known as Infant Start for six to 15-month-old infants who exhibited marked autism symptoms, such as decreased eye contact, social interest or engagement, repetitive movement patterns, and a lack of intentional communication.

The therapy is performed over a six-month period. Investigators believe a critical aspect of the program is the delivery of the intervention by the people who are most in tune with and spent the most time with the babies: the parents.

The article is co-authored by psychologists Drs. Sally J. Rogers and Sally Ozonoff and is found online in the Journal of Autism and Developmental Disorders.

“Most of the children in the study, six out of seven, caught up in all of their learning skills and their language by the time they were two to three,” said Rogers, the study’s lead author and the developer of the Infant Start therapy. “Most children with ASD are barely even getting diagnosed by then.”

“For the children who are achieving typical developmental rates, we are essentially ameliorating their developmental delays,” Rogers said.

“We have speeded up their developmental rates and profiles, not for every child in our sample, but for six of the seven.”

Rogers credited the parents in the small, pilot study with making the difference.

“It was the parents — not therapists — who did that,” she said.

“Parents are there every day with their babies. It’s the little moments of diapering, feeding, playing on the floor, going for a walk, being on a swing, that are the critical learning moments for babies. Those moments are what parents can capitalize on in a way that nobody else really can.”

Identification of Autism at Early Age is Critical

Children diagnosed with autism typically receive early intervention beginning at three to four years, six to eight times later than the children who participated in the study.

But the earliest symptoms of autism may be present before the child’s first birthday.

Infancy is the time when children first learn social interaction and communication, so autism researchers and parents of children with the condition have been working to identify autism and begin intervention sooner.

Effective autism treatment relies on early detection so that a child can begin therapy as soon as possible, to prevent or mitigate the full onset of symptoms and sometimes severe and lifelong disability.

“We were very fortunate to have this treatment available for the affected infants identified through our study,” said Ozonoff.

“We want to make referrals for early intervention as soon as there are signs that a baby might be developing autism,” Ozonoff said.

“In most parts of the country and the world, services that address autism-specific developmental skills are just not available for infants this young.”

Of the seven babies in the study, four were part of the Infant Sibling Study. In addition to these four, the other three children were referred by community parents. The treatment group was compared with four other groups of children that included:

  • High-risk children with older siblings with autism who did not develop autism;
  • Low-risk children who were the younger siblings of typically developing children;
  • Infants who developed autism by the age of three;
  • Children who also had early autism symptoms but chose to receive treatment at an older age.

The treatment was based on the highly successful Early Start Denver Model (ESDM) intervention developed by Rogers and her colleague, Dr. Geraldine Dawson, professor of psychiatry, psychology, and pediatrics at Duke University in North Carolina.

ESDM is usually provided in the home by trained therapists and parents during natural play and daily routines.

Parents were coached to concentrate their interactions on supporting their infants’ individualized developmental needs and interests, and embedded these practices into all of their play and caretaking, focusing on creating pleasurable social routines to increase their children’s opportunities for learning.

Parents were encouraged to follow their infants’ interests and subtle cues and gauge activities in ways that optimized their child’s attention and engagement. The intervention focused on increasing:

  • Infant attention to parent faces and voices;
  • Parent-child interactions that attract infants’ attention, bringing smiles and delight to both;
  • Parent imitation of infant sounds and intentional actions;
  • Parent use of toys to support, rather than compete with, the child’s social attention.

The treatment sessions included:

  • Greeting and parent progress sharing;
  • A warm-up period of parent play, followed by discussion of the activity and intervention goals;
  • Discussion of a new topic, using a parent manual;
  • Parents interacting in a typical daily routine with their child while fostering social engagement, communication, and appropriate play, with coaching from therapists;
  • Parents practicing the approach with their child across one or two additional home routines with toys or caregiving activities.

All of the participants who received treatment were between six and 15 months old, lived within a one-hour drive of the MIND Institute, and came from families where English was the primary language.

They had normal vision and hearing and no significant medical conditions. All received assessments prior to their participation and at multiple points throughout the study.

The treatment group of seven children received scores on the Autism Observation Scale for Infants (AOSI) and the Infant-Toddler Checklist that indicated they were highly symptomatic and at risk of developing ASD.

Their symptoms also elicited clinical concern from professors Rogers and Ozonoff.

During the study, both the children’s and parents’ responses to the intervention were measured.

Treatment began immediately after enrollment and consisted of 12 one-hour sessions with infant and parent. It was followed by a six-week maintenance period with biweekly visits, and follow-up assessments at 24 and 36 months.

The treatment sessions focused on parent–child interactions during typical daily life and provided parent coaching as needed to increase infant attention, communication, early language development, play, and social engagement.

The children who received the intervention had significantly more autism symptoms at nine months, but significantly lower autism severity scores at 18- to 36-months of age, when compared with a small group of similarly symptomatic infants who did not receive the therapy.

Overall, the children who received the intervention had less impairment in terms of autism diagnosis, and language and development delays than either of the other affected groups.

Given the preliminary nature of the findings, the study only suggests that treating these symptoms so early may lessen problems later.

Larger, well-controlled studies are needed to test the treatment for general use.

However, the researchers said that this initial study is significant because of the very young ages of the infants, the number of symptoms, and delays they exhibited early in life, the number of comparison groups involved, and because the intervention was low intensity and could be carried out by the parents in everyday routines.

“I am not trying to change the strengths that people with ASD bring to this world,” Rogers said when asked whether she is seeking to “cure” autism.

“People with ASD contribute greatly to our culture,” she said. “The diversity of human nature is what makes us a powerful and strong species. We are trying to reduce the disability associated with ASD.”

“My goal is for children and adults with autism symptoms to be able to participate successfully in everyday life and in all aspects of the community in which they want to participate: to have satisfying work, recreation, and relationships, education that meets their needs and goals, a circle of people they love, and to be generally happy with their lives.”

Source: University of California – Davis Health System

Therapist examining infant photo by shutterstock.

Pilot Program Finds Early Autism Intervention Beneficial

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Pilot Program Finds Early Autism Intervention Beneficial. Psych Central. Retrieved on November 30, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 10 Sep 2014)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
Published on Psych All rights reserved.