New research from the UK posits that more accurate tests could be created to diagnose diseases such as Alzheimer’s or memory problems stemming from head injuries.
Identification of memory disorders in the early stages can lead to earlier and more effective interventions.
Researchers investigated the components of memory using a combination of tests and neuroimaging.
The strategy could lead to a new diagnostic tool for distinguishing between different types of dementia, memory damage from stroke, or forms of amnesia caused by head trauma.
Dr. Louis Renoult, a lecturer at the University of East Anglia (UEA) said, “We are creating a new model of how we look at memory that’s more nuanced and gives us a better picture of how memories, particularly long-term memories, are imprinted.”
The findings, published in The Journal of Cognitive Neuroscience, are part of an international project with contributions from academics at the University of Ottawa, the State University of New York College at Old Westbury, and the Rotman Research Institute, Baycrest, Toronto.
Dr Renoult said, “If patients lose semantic memory, they struggle with knowledge of everyday objects in the world, and have trouble communicating.
“But if you provide some personal application to those objects — for example showing a dog to someone who kept a dog as a pet — the patient may demonstrate they’ve retained memory of that object.
“The research shows this retained memory performance may result from the brain’s automatic activation of personal episodes by related knowledge.
“We haven’t previously been aware of this intermediate form of memory, which combines semantic knowledge with autobiographical, or ‘episodic’ memory.
“The hope is that advanced methods could be developed to test this newly discovered intermediate form of memory, leading to better approaches to rehabilitation.”
The research was undertaken in 2011-2012 and involved a cohort of 19 healthy subjects.
Source: University of East Anglia