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ADHD Meds Shown to Not Increase Suicide Risk – And May Protect Against It

ADHD Meds Shown to Not Increase Suicide Risk – And May Protect Against It

A comprehensive review of a national patient registry shows that drug therapy for attention-deficit hyperactivity disorder (ADHD) does not increase suicide attempts or suicide, as was previously feared.

In fact, according to Swedish researchers from the Karolinska Institute, the ADHD medications may have a protective effect.

“Our work in several ways shows that most likely there is no link between treatment with ADHD drugs and an increased risk of suicide attempts or suicide. The results rather indicate that ADHD drugs may have a protective effect,” said Henrik Larsson, Ph.D., researcher at the Department of Medical Epidemiology and Biostatistics, who headed the study.

Earlier research has indicated that ADHD drug treatment would increase the occurrence of suicidal thoughts. But these studies have been small scale and/or the methods used have been limited, which make the results uncertain.

To gain clarity in this matter, Swedish researchers have now used national patient registers to identify all patients in Sweden diagnosed with ADHD between 1960 and 1996; a total of 37,936 individuals.

These people were then followed over the period 2006-2009, in terms of drug treatment and events that could be linked to suicide attempts and suicide.

Among other things, the study compared the rate of suicidal behaviors while the patients were receiving ADHD medication, as compared with the rate for the same patients while not receiving medication.

Using this design the researchers were able to determine that there was no evidence to support that ADHD drug therapy would increase the risk of suicide attempts/suicide.

One strong point of the study now being published is that all the individuals were compared to themselves, as this allowed the researchers to take into account the differences between those taking the drugs and those who do not.

“Many epidemiological studies on the risks related to drugs fail to adjust for the differences between individuals who take the drugs and those who do not. This is a critical limitation given that the individuals on medication are usually more severely ill than the others,” said Larsson.

The study has been published in the British Medical Journal (BMJ).

Source: Karolinska Institute

ADHD Meds Shown to Not Increase Suicide Risk – And May Protect Against It

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). ADHD Meds Shown to Not Increase Suicide Risk – And May Protect Against It. Psych Central. Retrieved on March 25, 2019, from
Scientifically Reviewed
Last updated: 8 Aug 2018
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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