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Prenatal Smoking + Genetics = Kids’ Aggressive Behavior

A new study finds evidence that prenatal smoking coupled with a genetic risk for behavioral problems could increase aggressive behavior in children — especially in girls.

Researchers point out that the findings do not suggest that all children exposed to prenatal smoking will have behavioral problems.

“One possible explanation for this is that the effect of prenatal smoke exposure depends on the presence of ‘triggering influence;’ in this case, we investigated whether genetic risk factors might act as just such a trigger,” says Brian Boutwell, Ph.D., senior author on the study.

The study was based on a nationally representative sample of 1,600 twins, including identical and fraternal pairs, collected during early childhood.

Researchers found that children exposed to prenatal smoking, and who also had an increased genetic propensity for antisocial behavior, exhibited the most pronounced conduct problems during childhood.

Interestingly, this gene-environment interaction was most pronounced in females.

Experts believe the study findings demonstrate that prenatal environmental experiences may influence future behavioral problems in children, especially in combination with the presence of genetic risk factors.

Ultimately, the study presented four key findings:

• Genetic risk factors increase behavioral problems in children;
• Prenatal maternal smoking, when taken in isolation, did not appear to directly result in behavioral problems;
• The influence of genetic risk factors on behavior problems were most pronounced for children exposed to prenatal smoking;
• The interaction between genetic factors and prenatal smoking was isolated to females.

The current research underscores the link between genetic factors and antisocial behaviors.

Boutwell said that while most research focuses on environmental factors, such as the family and neighborhoods, it is important to explore alternative environments, such as prenatal experiences, to gain a better understanding of the origins of problem behaviors.

“Social scientists have spent decades looking at what happens with parents and the family to try and determine why some children develop behavioral problems and others don’t,” said Boutwell.

“While we are not saying that family environments are completely unimportant, environmental experiences encompass far more than just parenting.

“It is possible, in fact, than other environmental experiences may matter just as much, and perhaps more in some cases, for development than simply what happens inside the home between parents and children.”

Source: Sam Houston State University

Prenatal Smoking + Genetics = Kids’ Aggressive Behavior

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Prenatal Smoking + Genetics = Kids’ Aggressive Behavior. Psych Central. Retrieved on September 28, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 24 Apr 2014)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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