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Attachment Anxiety Lowers Immunity — But Can Be Overcome

Attachment Anxiety Lowers Immunity -- But Can Be Overcome  We all understand that concern over a relationship can influence our mental health. Anxiety, depression, appetite and sleep loss, and a host of other symptoms stem from our psychological distress.

A new study clarifies that concerns and anxieties about one’s close relationships can fuel chronic stress that compromises our immunity from infection and other physical conditions.

In the study, researchers asked married couples to complete questionnaires about their relationships. In addition, saliva and blood samples were collected to test participants’ levels of a key stress-related hormone and numbers of certain immune cells.

Scientists specifically studied attachment (or separation) anxiety. Individuals who are on the high end of the attachment anxiety spectrum are excessively concerned about being rejected, have a tendency to constantly seek reassurance that they are loved, and are more likely to interpret ambiguous events in a relationship as negative.

Researchers discovered married partners who were more anxious produced higher levels of cortisol, a steroid hormone that is released in response to stress, and had fewer T cells — important components of the immune system’s defense against infection — than did participants who were less anxiously attached.

“Everyone has these types of concerns now and again in their relationships, but a high level of attachment anxiety refers to people who have these worries fairly constantly in most of their relationships,” said Lisa Jaremka, lead author of the study.

Although the genesis of attachment anxiety is unknown, some scientists theorize that attachment anxiety can be traced to inconsistent care during one’s infancy.

Jaremka’s research suggests that whatever the origin, people with attachment anxiety can change. “It’s not necessarily a permanent state of existence,” she said.

In the study, Jaremka and colleagues tested the health effects of attachment anxiety on 85 couples who had been married for an average of more than 12 years. Most participants were white, and their average age was 39 years.

The participants completed a questionnaire called The Experiences in Close Relationships scale. They also reported general anxiety symptoms and their sleep quality. Researchers collected saliva samples over three days and blood samples over two days.

Participants with higher attachment anxiety produced, on average, 11 percent more cortisol than did those with lower attachment anxiety.

The more anxiously attached participants also had between 11 percent and 22 percent fewer T cells than did less anxiously attached partners. Four T-cell markers were analyzed in the study.

“Everyone has these types of concerns now and again in their relationships, but a high level of attachment anxiety refers to people who have these worries fairly constantly in most of their relationships.”

The combined findings make sense and are likely related, Jaremka said, because cortisol can have immunosuppressive effects – meaning it can inhibit production of these very same T cells.

Previous research has suggested that reduced T-cell levels can impair the immune response to vaccines and that low levels of the cells are a hallmark of an aging immune system.

One theory suggests attachment anxiety is a phenomenon related to childhood development. Experts hypothesize that at a very young age, children learn whether or not their primary caregivers will respond when the children are in distress.

If caregivers are responsive, children learn they can rely on other people. If care is inconsistent or neglectful, children can develop feelings of insecurity that might manifest as attachment anxiety later in life.

Though she knows of no research-based advice about how to shed these feelings of insecurity, Jaremka said it is clear that people can change.

“Most research that does exist in this area supports the idea that being in very caring, loving, close relationships might be a catalyst to change from being very anxious to not,” she said.

The study appears online in the journal Psychological Science and is scheduled for a future print publication.

Source: Ohio State University

Couple looking at each other photo by shutterstock.

Attachment Anxiety Lowers Immunity — But Can Be Overcome

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Attachment Anxiety Lowers Immunity — But Can Be Overcome. Psych Central. Retrieved on November 29, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 12 Feb 2013)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
Published on Psych All rights reserved.