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Using Music to Reset the Sleepless Brain

Using Music to Reset the Sleepless BrainSleep problems are common among Americans with half of the population suffering from insomnia. New pilot research seeks to restore sleep using a noninvasive approach that uses music to balance brain activity.

Americans try everything to aid sleep with common solutions ranging from warm milk to melatonin pills to prescription medications — with varying degrees of success and side effects.

New research from Wake Forest Baptist Medical Center takes a unique approach of using musical tones to “reset” the brain and effectively reduce insomnia.

Charles H. Tegeler, M.D., professor of neurology at Wake Forest Baptist and principal investigator of the study, explained how the technology works.

“The human brain is made up of the left and right hemispheres that work together as parallel processors. When a person undergoes trauma or a major stressor, their autonomic survival responses kick in and the brain can become unbalanced.

“If those imbalances persist, symptoms such as insomnia can result. Our study looked at a new technology that is intended to facilitate greater balance and harmony in brain frequencies, which may result in improved symptoms.”

The new technology is called HIRREM — HIgh-resolution, Relational, Resonance-based, Electroencephalic Mirroring. It’s commercially known as Brainwave Optimization.

The non-invasive procedure uses a system that is designed to reflect the brain’s frequencies back to itself using musical tones.

Researchers believe resonance between the musical tones and the electrical energy in a person’s brain can bring balance to the two hemispheres of the brain.

Investigators tracked changes in the Insomnia Severity Index (ISI) which measures the severity of sleep disruption using a zero-to-28 point scale. When the study began, participants reported a median ISI between 18.7 and 18.9, which is considered moderate-to-severe insomnia.

Researchers found that the HIRREM group had a 10.3 point drop in ISI, improved insomnia symptoms and, clinically moved into a category of “no insomnia” or “sub-threshold insomnia.”

The control subjects, who continued their existing insomnia treatment without HIRREM, showed no change in ISI. However, when the intervention was flipped exposing the control group to HIRREM therapy, the results were indistinguishable from those of the original HIRREM group.

This unblinded, wait-list control, crossover study enrolled 20 participants (14 women and 6 men). Ten people were randomized to receive HIRREM sessions, plus usual care; the remaining 10 were assigned to the wait-list control group.

At the beginning of the study, researchers determined the symmetry, or balance, in amplitude and frequencies between the brain hemispheres and data collection. In addition, a subject’s ISI scores and other measures including blood pressure and neurocognitive function tests were documented.

Study participants randomized to HIRREM underwent eight to 12 sessions that each lasted between 60-90 minutes. The sessions involved reclining in a zero gravity chair and placing sensors over locations on both sides of the scalp.

A musical tone, determined by a mathematic algorithm and based on the dominant frequency in a floating middle range of the participant’s EEG frequencies, was played back to the participant through ear buds. Resonance between musical tones and oscillating brain circuits is designed to allow the brain to auto-calibrate, moving towards better balance, with associated improvement in symptoms.

While the study results are promising, researchers note that the investigation had limitations. To begin with, the sample or study size was small and the absence of a sham-placebo control group prevented blinding.

This means it is possible that the changes observed with HIRREM could be due to a placebo effect. In addition, because HIRREM therapy involves social interaction and relaxation, there may be other non-specific mechanisms for improvement, in addition to the tonal mirroring.

Although the researchers believe that the degree of improvement and length of time it persisted (for four weeks after the last session) suggests real change through HIRREM, Tegeler is planning a larger clinical trial using a sham placebo, to confirm the HIRREM effect and further explore the technology.

The study is published online ahead of print in the journal Brain and Behavior. It was funded by a $26,696 grant from Brain State Technologies, Scottsdale, Ariz., the company that owns the technology used in the study.

Source: Wake Forest Baptist Medical Center

Using Music to Reset the Sleepless Brain

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Using Music to Reset the Sleepless Brain. Psych Central. Retrieved on December 2, 2020, from
Scientifically Reviewed
Last updated: 8 Aug 2018 (Originally: 21 Nov 2012)
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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