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Appetite Hormones Influence Weight Regain

Many, if not a majority of dieters have experienced a yo-yo diet experience where weight is lost and then regained.

According to a new study the levels of appetite hormones in the body prior to dieting may serve as a predictor of weight regain after dieting.

“Treating obesity with drugs or dietary programs can be very effective in the short-term, but the long-term success of maintaining the weight lost is usually poor,” said Ana Crujeiras, PhD.

“Our study sheds light on how the appetite hormones leptin and ghrelin affect weight regain after weight loss. This knowledge could be used as a tool to personalize weight-loss programs that could guarantee success in keeping off the weight.”

The research will be published in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

In this study, researchers evaluated a group of 104 obese or overweight men and women during an eight-week low-calorie diet and again 32 weeks after treatment.

Researchers measured body weight as well as plasma fasting ghrelin, leptin and insulin concentrations before, during and after dieting.

They found that subjects with higher plasma leptin and lower ghrelin levels before dieting were more prone to regain weight lost after dieting and that these hormone levels could be proposed as biomarkers for predicting obesity treatment outcomes.

“We believe this research is of foremost relevance in clinical terms as it may indicate that the outcome of weight therapy may be pre-conditioned,” said Crujeiras.

“Furthermore, our findings may provide endocrinology and nutrition professionals a tool to identify individuals in need of specialized weight-loss programs that first target appetite hormone levels before beginning conventional dietary treatment.”

Source: The Endocrine Society

Appetite Hormones Influence Weight Regain

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2016). Appetite Hormones Influence Weight Regain. Psych Central. Retrieved on November 18, 2018, from https://psychcentral.com/news/2010/09/13/appetite-hormones-influence-weight-regain/18078.html

 

Scientifically Reviewed
Last updated: 7 Jul 2016
Last reviewed: By John M. Grohol, Psy.D. on 7 Jul 2016
Published on PsychCentral.com. All rights reserved.