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Blood Test Predicts Age of Menopause

Blood Test Predicts Age of MenopauseResearchers report they have developed a method to predict when women will begin menopause.

The finding was delivered by Dr. Fahimeh Ramezani Tehrani at the 26th annual meeting of the European Society of Human Reproduction and Embryology in Rome.

Tehrani says her findings have implications for women and their doctors. If the results of the research are supported by larger studies, it means that women will be able to discover early on in their reproductive life what their expected age at menopause will be, so that they can plan when to start a family.

Researchers determined the average difference between the predicted age and the actual age that the women in their study reached menopause was only a third of a year, and the maximum margin of error was between three and four years.

By taking blood samples from 266 women, aged 20-49, who had been enrolled in the much larger Tehran Lipid and Glucose Study, Dr. Ramezani Tehrani and her colleagues were able to measure the concentrations of a hormone that is produced by cells in women’s ovaries — anti-Mullerian Hormone (AMH).

AMH controls the development of follicles in the ovaries, from which oocytes (eggs) develop and it has been suggested that AMH could be used for measuring ovarian function. The researchers took two further blood samples at three yearly intervals, and they also collected information on the women’s socioeconomic background and reproductive history.

In addition, the women had physical examinations every three years.

The Tehran Lipid and Glucose Study is a prospective study that started in 1998 and is still continuing.

Dr. Ramezani Tehrani was able to use a statistical model to identify AMH levels at different ages that would predict if women were likely to have an early menopause (before the age of 45). She found that, for instance, AMH levels of 4.1 ng/ml or less predicted early menopause in 20-year-olds, AMH levels of 3.3 ng/ml predicted it in 25-year-olds, and AMH levels of 2.4 ng/ml predicted it in 30-year-olds.

In contrast, AMH levels of at least 4.5 ng/ml at the age of 20, 3.8 ngl/ml at 25 and 2.9 ng/ml at 30 all predicted an age at menopause of over 50 years old. The researchers found that the average age at menopause for the women in their study was approximately 52.

Source: European Society of Human Reproduction and Embryology

Blood Test Predicts Age of Menopause

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Blood Test Predicts Age of Menopause. Psych Central. Retrieved on June 20, 2018, from https://psychcentral.com/news/2010/06/28/blood-test-predicts-age-of-menopause/15149.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
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