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Genetics and Psychology Combine for ADHD

Genetics and Psychology Combine for ADHDA new study suggests ADHD may be caused by alterations in the nerve transmission system along with a tendency to experience psychosocial distress.

Researchers found that ADHD behaviors in children and adolescents were associated with interactions between low and high serotonin activity and self-blame in relation to inter-parental conflict.

Molly Nikolas, from Michigan State University worked with a team of researchers to study a key serotonin genetic region, 5HTTLPR, and the tendency for children to blame themselves for parental arguments.

In the study of 304 youths, researchers found that those children who reported more self-blame, and had variants of the region associated with both high and low serotonergic activity, had more ADHD symptoms.

According to the authors, “To date, studies have mostly focused on the effects of genetic and environmental influences on ADHD separately.

“Our work examines the interaction between a specific gene variant and a family environmental risk factor in order to determine their roles in the development of ADHD via behavioral and emotional dysregulation in children.”

5HTTLPR is a functional genetic region responsible for regulating the production of a protein that transports the neurotransmitter serotonin; it has previously been linked to a range of neuropsychiatric disorders and personality traits.

Tendency to self-blame was assessed by questionnaire.

The authors stated, “Overall, these results complement growing evidence suggesting that 5HTTLPR variants confer a liability for ADHD that is activated in particular environments, rather than conferring risk for ADHD directly.”

The study is found in BioMed Central’s open access journal Behavioral and Brain Functions.

Source: BioMed Central

Genetics and Psychology Combine for ADHD

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Genetics and Psychology Combine for ADHD. Psych Central. Retrieved on December 11, 2018, from https://psychcentral.com/news/2010/04/16/genetics-and-psychology-combine-for-adhd/12892.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
Published on PsychCentral.com. All rights reserved.