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Not Interested in Having a Good Time?

A new study suggests a decreased desire for pleasure may be a key predisposing factor for major depression.

The research is in contrast to the long-held notion that those suffering from depression lack the ability to enjoy rewards, rather than the desire to seek them.

Vanderbilt psychologists Michael Treadway and David Zald led the study published by current edition of the online journal PLoS One.

“This initial study shows that decreased reward processing, which is a core symptom of depression, is specifically related to a reduced willingness to work for a reward,” Treadway, a graduate student in psychology, said.

Decreased motivation to seek and experience pleasurable experiences, known as anhedonia, is a primary symptom of major depressive disorder.

Anhedonia is less responsive to many antidepressants and often persists after other symptoms of depression subside.

However, understanding the different components of anhedonia – the desire to obtain something pleasurable versus experiencing pleasure – has been difficult for researchers to determine in humans.

“In the last decade and a half, animal models have found that the neurotransmitter dopamine, long known to be involved in reward processing, is involved in craving or motivation, but not necessarily enjoyment,” Treadway said.

“To date, research into reward processing in individuals with anhedonia has focused on enjoyment of rewards, rather than assessing the drive to work for them. We think this task is one of the first to do that.”

Treadway and his colleagues devised the Effort-Expenditure for Rewards Task, or EEfRT, to explore the role of reduced desire and motivation in individuals reporting symptoms of anhedonia.

EEfRT involved having individuals play a simple video game that gave them a chance to choose between two different tasks, one hard, one difficult, to obtain monetary rewards. Participants were eligible but not guaranteed to receive money each time they completed a task successfully.

The “hard” task required pressing a button 100 times within 21 seconds using one’s non-dominant little finger and carried a potentially higher reward than the easy task, which required pressing a button 30 times in seven seconds using one’s dominant index finger.

The subjects were told at the beginning of each trial whether they had a high, medium or low probability of winning a prize if they successfully completed the trial. The participants could choose which trials they completed and were given 20 minutes to perform as many tasks as possible.

The researchers found that subjects who reported symptoms consistent with anhedonia were less willing to make choices requiring greater effort in exchange for greater reward, particularly when the rewards were uncertain.

“Consistent with our hypotheses, we found that individuals with self-reported anhedonia made fewer hard-task choices,” the authors wrote. “These findings are consistent with theoretical models linking anhedonia to decreased (dopamine levels).”

“By addressing the motivational dimension of anhedonia, our findings suggest a plausible theoretical connection between dopamine deficiency and reward processing in depression, which may eventually help us better understand how anhedonia responds to treatment,” Treadway said.

Source: Vanderbilt University

Not Interested in Having a Good Time?

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Not Interested in Having a Good Time?. Psych Central. Retrieved on June 23, 2018, from https://psychcentral.com/news/2009/08/14/not-interested-in-having-a-good-time/7760.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
Published on PsychCentral.com. All rights reserved.