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Eye Disease Linked with Cognitive Impairment

New research suggests older adults with advanced cognitive decline appear more likely to be in the early stages of age-related macular degeneration.

According to the report in the May issue of Archives of Ophthalmology, macular degeneration appears to accompany low scores on tests of cognitive function, including thinking, learning and memory among older adults.

Age-related macular degeneration (AMD) — the leading cause of visual impairment in industrialized nations — has long been thought to share a common pathway with Alzheimer’s disease, according to background information in the article.

First, both conditions involve similar changes in the brain and eye, including the buildup of protein fragments known as beta-amyloid.

“Second, clinical studies suggest that AMD and Alzheimer’s disease share similar vascular risk factors, such as hypertension [high blood pressure] and cigarette smoking,” the authors write.

“Both AMD and Alzheimer’s disease have been linked to an increased risk of stroke.”

Michelle L. Baker, M.D., of the University of Melbourne, Victoria, Australia, and colleagues assessed 2,088 individuals age 69 to 97. Participants underwent cognitive testing, retinal photography for the detection of AMD and an extensive assessment of artery disease and its risk factors (including blood pressure, smoking status and body mass index).

After controlling for age, sex, race and the center at which they participated in the study, the one-fourth of individuals with the lowest scores on one cognitive test were twice as likely to have early-stage AMD as were individuals with higher scores.

However, there was no association between AMD and scores on a second cognitive test, dementia or Alzheimer’s disease.

“In conclusion, we found an association between low cognitive function and early AMD in this older population,” the authors write.

“These data, along with others, provide further support that AMD and cognitive impairment may share similar complex pathogenesis [development] and risk factors.”

Eye Disease Linked with Cognitive Impairment

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Eye Disease Linked with Cognitive Impairment. Psych Central. Retrieved on September 25, 2018, from https://psychcentral.com/news/2009/05/12/eye-disease-linked-with-cognitive-impairment/5848.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
Published on PsychCentral.com. All rights reserved.