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Children At Risk If Parents Bipolar

Children and teens of parents with bipolar disorder appear to have an increased risk of early-onset bipolar disorder, mood disorders and anxiety disorders.

As many as 60 percent of patients with bipolar disorder experience symptoms before age 21, according to background information in the article.

Identifying the condition early may improve long-term outcomes, potentially preventing high psychosocial and medical costs. Having family members with bipolar disorder is the best predictor of whether an individual will go on to develop the condition, the authors note.

“Therefore, carefully evaluating and prospectively following the psychopathology of offspring of parents with bipolar disorder and comparing them with offspring of parents with and without non-bipolar disorder psychopathology, are critical for identifying the early clinical presentation of bipolar disorder,” they write.

Boris Birmaher, M.D., of Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, and colleagues compared 388 offspring (ages 6 to 18) of 233 parents with bipolar disorder to 251 offspring of 143 demographically matched control parents.

Parents were assessed for psychiatric disorders, family psychiatric history, family environment and other variables, and were also interviewed about their children. Children were assessed directly for bipolar disorder and other psychiatric disorders by researchers who did not know their parents’ diagnoses.

Compared with the offspring of control parents, children of parents with bipolar disorder had an increased risk of having a bipolar spectrum disorder (41 or 10.6 percent vs. two or 0.8 percent) and having any mood or anxiety disorder.

Children in families where both parents had bipolar disorders also were more likely than those in families containing one parent with bipolar disorder to develop the condition (four of 14 or 28.6 percent vs. 37 of 374 or 9.9 percent); however, their risk for other psychiatric disorders was the same as offspring of one parent with bipolar disorder.

“Consistent with the literature, most parents with bipolar disorder recollected that their illness started before age 20 years and about 20 percent had illness that started before age 13 years,” the authors write.

“In contrast, most of their children developed their first bipolar disorder episode before age 12 years, suggesting the possibility that parents were more perceptive of their children’s symptoms early in life or perhaps that bipolar disorder has more penetrance and manifests earlier in new generations.”

The findings have important clinical implications, they note. “Clinicians who treat adults with bipolar disorder should question those who are parents about their children’s psychopathology to offer prompt identification and early interventions for any psychiatric problems that may be affecting the children’s functioning, particularly early-onset bipolar disorder,” they continue.

Further studies are needed to help determine the clinical, biological and genetic risk factors that may be modified to prevent the development of psychiatric disorders in the offspring of those with bipolar disorder.

The study is found in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Source: JAMA and Archives Journals

Children At Risk If Parents Bipolar

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Children At Risk If Parents Bipolar. Psych Central. Retrieved on July 22, 2018, from https://psychcentral.com/news/2009/03/03/children-at-risk-if-parents-bipolar/4497.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
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