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Diabetes Increases Alzheimer’s Risk

Researchers have discovered diabetics have a significantly greater risk of developing Alzheimer’s and other forms of dementia.

The findings emanate from a study of twins that found the risk of dementia is especially strong if the onset of diabetes occurs in middle age.

“Our results . . . highlighted the need to maintain a healthy lifestyle during adulthood in order to reduce the risk of dementia late in life,” explained Dr. Margaret Gatz, who directs the Study of Dementia in Swedish Twins.

In a study published in the January 2009 issue of Diabetes, Gatz and researchers from Sweden show that getting diabetes before the age of 65 corresponds to a 125 percent increased risk for Alzheimer’s disease.

Nearly 21 million people in the United States have diabetes, according to the American Diabetes Association, which publishes the journal.

This risk of Alzheimer’s disease or other dementia was significant for mid-life diabetics — as opposed to those who develop diabetes after 65 — even when controlling for family factors. In other studies, genetic factors and childhood poverty have been shown to independently contribute to the risk of both diabetes and dementia.

“Twins provide naturally matched pairs, in which confounding factors such as genetics and childhood environment may be removed when comparisons are made between twins,” explained Gatz, professor of psychology, gerontology and preventive medicine at the University of Southern California.

Indeed, the chances of a diabetic developing Alzheimer’s disease may be even greater in real life than in the study, the researchers write.

They identify several factors that might have led them to underestimate the risk of dementia and Alzheimer’s among those who develop diabetes before the age of 65.

Diabetes usually appears at a younger age than dementia does, the researchers note. Diabetes is also associated with a higher mortality rate, which may reduce the size of the sample of older adults. In addition, approximately 30 percent of older adults with diabetes have not been diagnosed.

The results of the study implicate adult choices such as exercise, diet and smoking, as well as glycemic control in patients with diabetes, in affecting risk for Alzheimer’s disease and diabetes, according to the researchers.

The sample for the study was 13,693 Swedish twins aged 65 or older in 1998, the year tracking for dementia began. Information about diabetes came from prior surveys of twins and linkage to hospital discharge registry data beginning in the 1960s.

Source: University of Southern California

Diabetes Increases Alzheimer’s Risk

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Diabetes Increases Alzheimer’s Risk. Psych Central. Retrieved on August 17, 2018, from https://psychcentral.com/news/2009/01/28/diabetes-increases-alzheimers-risk/3739.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
Published on PsychCentral.com. All rights reserved.