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Relationship Problems Increase Risk of Heart Disease

CoupleClassically, participation in a close social relationship has been found to convey health benefits and prolonged life for the partners.

New research challenges this presumption revealing women in relationships with negative aspects, such as conflict and adverse exchanges, appear to have an increased risk of heart disease than those with more positive close relationships.

The findings are published in the Archives of Internal Medicine, one of the JAMA/Archives journals.

“An extensive body of research shows that social relations are associated with better health and reduced risks of cardiovascular disease,” the authors write as background information in the article.

“However, contradictory findings on the health benefits of structural support and the limited protective effect of marital status against cardiovascular disease among women have stimulated further scientific inquiry into the quality of social relationships.”

Roberto De Vogli, Ph.D., M.P.H., and colleagues at University College London studied 9,011 British civil servants who completed a questionnaire about negative aspects of their close relationships either between 1989 and 1990 or between 1985 and 1988.

Although the questionnaire assessed up to four close relationships, the researchers focused specifically on the primary close relationship.

In addition, participants answered questions about how much emotional and practical support they received from that person on a regular basis. They were then followed for an average of 12.2 years to see if they experienced fatal or non-fatal coronary events, including heart attacks or chest pain.

Of the 8,499 individuals who did not have coronary heart disease at the beginning of the study and who provided sufficient information for the analysis, 589 reported a coronary heart disease event. After adjusting for other factors that influence heart disease risk—such as sociodemographic characteristics and health habits—those who experienced a high level of negativity in their close relationships were 1.34 times more likely to experience a coronary heart disease event than those with a low level of negative close relationships.

The association was weakened somewhat but still significant after the researchers adjusted for negative personality traits and depression. This suggests that emotions may partially mediate the association between negative relationships and heart disease.

“When one considers emotional factors and their biological translation into the body, research shows that negative marital interactions are associated with depression, often in combination with reduced self-esteem and/or higher levels of anger,” the authors write.

“These emotional reactions have been found to influence coronary heart disease through the cumulative ‘wear and tear’ on organs and tissues caused by the alterations of autonomic [involuntary] functions, neuroendocrine changes, disturbances in coagulation [blood clotting] and inflammatory and immune responses.”

Although women and those in lower employment grades were more likely to experience negative relationships, the associations with heart disease did not change based on sex or social position. In addition, heart disease risk was not associated with the level of emotional or practical support received.

“It is possible that negative aspects of close relationships are more important for the health of individuals because of the power of negative close relationships to activate stronger emotions (worrying and anxiety) and the consequent physiological effects,” the authors write.

“In contrast, other more positive forms of support may not affect the physiology of individuals in a measurable or clinically relevant way.”

Source: American Medical Association (AMA)

Relationship Problems Increase Risk of Heart Disease

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2018). Relationship Problems Increase Risk of Heart Disease. Psych Central. Retrieved on March 21, 2019, from
Scientifically Reviewed
Last updated: 8 Aug 2018
Last reviewed: By a member of our scientific advisory board on 8 Aug 2018
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