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Blood Inflammation Linked To Alzheimer’s

Researchers discover individuals who have a particular protein in their blood are at high risk to develop Alzheimer’s later in life. The proteins, called cytokines, are messengers that trigger inflammation.

The study is published in Neurology®, the scientific journal of the American Academy of Neurology.

Participants in the investigation, a part of the larger Framingham Heart Study, included 691 healthy people with an average age of 79.

Blood tests determined whether the participants had signs of inflammation. Then the participants were followed for an average of seven years. During that time, 44 of the participants developed Alzheimer’s disease.

The participants’ blood was tested for levels of cytokines, which are protein messengers that trigger inflammation.

Those with the highest amount of cytokines in their blood were more than twice as likely to develop Alzheimer’s disease as those with the lowest amount of cytokines. A total of 28 percent of the women and 30 percent of the men had high levels of cytokines, yet they made up 42 percent of the cases of Alzheimer’s disease.

“These results provide further evidence that inflammation plays a role in the development of Alzheimer’s disease,” said study author Zaldy Tan, MD, MPH, of Harvard Medical School in Boston.

“The production of these cytokines may be a marker of future risk of Alzheimer’s disease.”

The study was supported by grants from the National Institute of Neurological Disorders and Stroke, the National Institute on Aging, the Boston University Alzheimer’s Disease Center, and the National Heart, Lung and Blood Institute’s Framingham Heart Study.

Source: American Academy of Neurology

Blood Inflammation Linked To Alzheimer’s

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Blood Inflammation Linked To Alzheimer’s. Psych Central. Retrieved on September 19, 2018, from https://psychcentral.com/news/2007/05/29/blood-inflammation-linked-to-alzheimers/860.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
Published on PsychCentral.com. All rights reserved.