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Drug Improves Bone Density for Parkinson’s

Bone fractures among individuals with Parkinson disease is often a significant factor limiting mobility and at times triggering a downhill spiral. Researchers have discovered a drug used to strengthen bone has been found to help reduce the high incidence of hip fractures among people with Parkinson disease.

The study is published in the March 20, 2007, issue of Neurology®.

The two-year study involved 242 elderly men with Parkinson disease in Tokyo, Japan. Half of the group received the drug risedronate and vitamin D2. The remaining men received placebo and vitamin D2.

The study found the men taking risedronate were three times less likely to sustain a hip fracture compared to the placebo group.

Researchers also found bone mineral density (BMD) among men taking risedronate increased by 2.2 percent and decreased by nearly three percent in the placebo group. In addition, researchers found a biomarker for bone loss decreased by nearly 47 percent in the risedronate group and 33 percent in the placebo group.

“Prior to the study, these men had been experiencing a rapid rate of bone loss due to inactivity. Our findings show risedronate, along with vitamin D2, effectively controls the progression of osteoporosis, and reduces the risk of hip fractures,” said study author Yoshihiro Sato, MD, with Mitate Hospital in Tokyo.

Sato says the findings also show risedronate is stronger than the drug alendronate, which has been found in previous studies to reduce bone loss and prevent hip fractures in elderly women with Parkinson disease.

Side effects of risedronate included inflammation of the esophagus and abdominal pain, which eventually healed with appropriate therapy, according to the study.

Source: American Academy of Neurology

Drug Improves Bone Density for Parkinson’s

Rick Nauert PhD

Rick Nauert, PhDDr. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Dr. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy. His research efforts included the area of telehealth with a specialty in disease management.

APA Reference
Nauert PhD, R. (2015). Drug Improves Bone Density for Parkinson’s. Psych Central. Retrieved on June 18, 2018, from https://psychcentral.com/news/2007/03/21/drug-improves-bone-density-for-parkinsons/699.html

 

Scientifically Reviewed
Last updated: 6 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 6 Oct 2015
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