Home » Depression » In-Depth: Living with Depression

In-Depth: Living with Depression

What To Expect from Treatment

Treatment can consist of medication, psychotherapy or a combination of the two. Various practitioners, including psychologists, psychiatrists, licensed professional counselors and social workers, and primary care physicians can treat depression. Which professional and which treatment you choose is up to you.

“In our experience, fully half of patients can be managed exclusively in primary care. Many others would benefit from mental health consultation and some may need or prefer to be managed in mental health,” Dr. Dietrich said. Taking medication “can work on its own, is more accessible to many people and may require less frequent visits,” he said.

However, as Hollon points out, medication doesn’t correct the underlying propensity for depression or address the negative thinking and behavior. This can be especially problematic for patients with chronic depression.

Whatever the limits of medication and psychotherapy, each is effective in reducing depression symptoms. Some research has shown that a combination of the two is particularly powerful.


There are many types of psychotherapy; however, not all approaches are created equal. So it’s important to understand what approach your therapist is going to use. Whereas generic talk therapy has not been proven effective in treating depression, research consistently shows that cognitive-behavioral approaches and interpersonal therapy are successful.

“Depressed patients typically make specific errors in thinking and engage in unproductive behavioral patterns that lead to, maintain and can worsen depression,” said Oakley. When they walk in the door, clients typically have lots of evidence that they’ve screwed up in life and tend to blame themselves, said Hollon. It is these errors and evidence that cognitive behavioral approaches address.

Contrary to popular belief, these therapies don’t focus on the power of positive thinking. “I’d much rather see people be realistic instead of falsely optimistic,” said Hollon.

A large part of cognitive-behavioral approaches is investigating patients’ slew of negative evidence. “Patients learn how to examine the accuracy of their own beliefs, so they don’t get stuck with self-fulfilling prophecies,” said Hollon. For instance, instead of saying, “I didn’t get into college because I am stupid,” a patient examines the evidence and might realize that he didn’t get accepted because he only applied to one school or didn’t correctly complete the application.

Length of treatment ultimately depends on the severity of the depression, but cognitive-behavioral therapy (CBT) typically lasts from 12 to 24 sessions. “Patients can usually expect to see incremental changes in mood usually by the 12th session,” Oakley said.

In Hollon’s experience, patients typically start feeling better after a week or two, though the gains aren’t lasting. If Hollon doesn’t see “good improvement between four to six sessions” (if the depression isn’t severe or chronic), he wonders what’s missing. If you aren’t getting better, always ask why and don’t blame yourself, said Hollon. “It might be that your therapist isn’t pushing you forward.”

Overcoming Common Obstacles in Psychotherapy

Various hurdles can hinder progress in therapy. Here’s how to overcome them.

  • Be honest. Though it’s tough opening up to someone you don’t know about your innermost feelings, being honest with your therapist helps you make progress. If you aren’t comfortable disclosing information to your therapist, ask yourself why. If it’s the therapist who makes you uncomfortable, you might want to see someone else.
  • Be willing. It’s important to enter therapy with an open mind. For instance, even though you might experience a loss of interest in all activities, your therapist will encourage you to experiment with “things that previously brought joy, a sense of meaning or accomplishment,” said Oakley. Be willing to try these and other activities.
  • Remember you’re a team. Successful treatment involves both the patient and the therapist; it’s a collaborative process. “Patients assume an active participation in treatment, and assignments that are designed to build skills are an integral part of effective treatment,” said Oakley.
  • Speak up. A common obstacle to CBT is when patients don’t complete their assignments between sessions. “If your therapist is suggesting homework that seems like too much, discuss this with your therapist, who will most likely be open to the feedback and will work with you to make the between-session work manageable,” said Martell.
  • Consider your belief system. For some people, an ingrained belief system can impede treatment. For instance, an individual might feel that he’s doomed to a life of depression because of a family history of the disorder.
  • Remove mood from the driver’s seat. A common trap for depressed individuals is that they aren’t motivated to participate in activities that improve their mood. They become inactive and withdrawn, which worsens and maintains their depression, Oakley said. This is where it’s key not to let your feelings dictate what you do, he added.


Research shows that antidepressants are effective in reducing depression symptoms. But it’s important to understand that medication doesn’t work instantly or produce dramatic results. Most people will feel a positive impact in one to two weeks, but they won’t experience the full impact for one to two months, said Dr. Dietrich.

In the meantime, while you wait for the medication to start working, Dr. Dietrich suggests disciplining yourself to do the activities you used to enjoy. For instance, if you enjoyed visiting with friends before your depression, commit to inviting a friend over. He added, “You don’t need to be overly ambitious, but just get back in your groove.”

Keep in mind that the first medication you try may not be the right one for you. “Most people who start on one hypertension medicine will need to take a different or an additional medication. It’s not that much different for depression,” Dr. Dietrich said. In fact, trying several antidepressants and adjusting dosage is something doctors expect. So it’s important not to get discouraged if the first medication doesn’t work.

Common Concerns about Medication

Be sure to discuss with your doctor any concerns about taking medication. Some common worries are listed below.

  • They have significant side effects. All medications, whether they’re for depression, hypertension or the common cold, have side effects. However, “there are enough different choices of medication to find a minimal pattern of side effects” for each individual, Dr. Dietrich said. Also, your doctor can help shrink the impact of some side effects. For instance, if you have trouble sleeping, the physician might advise you to take your medication in the morning.
  • I’ll have to take them for life. It’s actually less common for people to take medication long-term. Instead, for most people depression is an acute, intermittent episode, which requires medication for six to nine months, Dr. Dietrich said. Those who have experienced more than one depressive episode may need a longer course of medication.

    Individuals who “achieve remission stay there for a period of time. If two to three years later, life becomes difficult, you just need to have treatment again,” Dr. Dietrich said.

  • They’re addictive. These medications don’t cause physical or psychological dependence or withdrawal symptoms. However, abruptly stopping medication can result in “discontinuation syndrome,” which occurs in about 20 percent of patients who take antidepressants for at least six weeks, according to the American Family Physician.

    Discontinuation syndrome is a series of symptoms such as flu-like symptoms, anxiety, dizziness, insomnia, blurred vision and hallucinations. The severity of these symptoms varies by person.

  • They increase the risk for suicide. Antidepressants do carry a black box warning, indicating an increased risk for suicidal thoughts and behaviors. However, this seems to be true for patients in their teens and early 20s and less true for adults, Dr. Dietrich said. Though patients should be monitored closely, he believes this risk is “short term, not very common and overplayed.”

What You Can Do To Ensure Effective Treatment

There are several key ways you can increase the chances that your medication will work more effectively.

  • Take medication as prescribed. Follow your doctor’s specific instructions on taking your medicine. Also, because newer antidepressants have tolerable side effects and work so well, patients tend to want to stop taking them, said Hollon. Discontinuing medication abruptly on your own, however, can be risky: You can return to feeling depressed and go through discontinuation syndrome. If you’re interested in discontinuing, talk with your doctor, so he or she can properly guide you through tapering off the medication.
  • Speak up. Raise any concerns or questions with your doctor. Tell your doctor about how the medication is working. Are you feeling any better or worse? What kind of side effects are you experiencing? Being open helps your doctor provide you with the best treatment.
In-Depth: Living with Depression

Margarita Tartakovsky, M.S.

Margarita Tartakovsky, M.S. is an Associate Editor and regular contributor at Psych Central. Her Master's degree is in clinical psychology from Texas A&M University. In addition to writing about mental disorders, she blogs regularly about body and self-image issues on her Psych Central blog, Weightless.

APA Reference
Tartakovsky, M. (2018). In-Depth: Living with Depression. Psych Central. Retrieved on October 23, 2019, from
Scientifically Reviewed
Last updated: 8 Oct 2018
Last reviewed: By a member of our scientific advisory board on 8 Oct 2018
Published on Psych All rights reserved.