Drug companies withheld information showing antidepressants were ineffective and could be harmful to children and should have issued warnings on their products, researchers said on Friday.
Health authorities in Britain and the United States have voiced concern or advised doctors not to prescribe the drugs known as selective serotonin reuptake inhibitors (SSRIs) to children under 18 because of a potential suicide risk.
Scientists who conducted a review of six published and six unpublished trials about their use in children say companies had been aware of problems but did not reveal them.
Surprising? Hardly. I first noted this issue back in 1996, in an editorial entitled Science’s Dirty Secret, but most graduate students become aware of the bias in research in their first year. I’m hardly the first to realize this conclusion, either. Other researchers have been saying the same thing for years.