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SSRI Augmentation

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I was on 150mg sertraline for many years and doing well. My psychiatrist agreed that I could come off. Unfortunately, my depression and anxiety returned as several major life stressors emerged. The dose was increased to 200mg and 1mg of aripiprazole was added. My doc said it would “jump start” the sertraline and might not be needed long term. In your experience, can an augmenting drug “jump start” an SSRI and then be discontinued? (From the USA)

SSRI Augmentation

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I think it is important to follow your physician’s lead on this while keeping in mind the potential pros and cons. I can give you medical advice because I am a psychologist and recommend you check out these studies to make a fully informed decision:

SSRI Augmentation

Daniel J. Tomasulo, PhD, TEP, MFA, MAPP

Dan Tomasulo Ph.D., TEP, MFA, MAPP teaches Positive Psychology in the graduate program of Counseling and Clinical Psychology at Columbia University, Teachers College and works with Martin Seligman, the Father of Positive Psychology in the Masters of Applied Positive Psychology (MAPP) program at the University of Pennsylvania. He is Director of the New York Certification in Positive Psychology for the Open Center in New York City and on faculty at New Jersey City University. Sharecare has honored him as one of the top 10 online influencers on the topic of depression. For more information go to: He also writes for Psych Central's Ask the Therapist column and the Proof Positive blog.

APA Reference
Tomasulo, D. (2018). SSRI Augmentation. Psych Central. Retrieved on May 18, 2019, from
Scientifically Reviewed
Last updated: 8 May 2018
Last reviewed: By a member of our scientific advisory board on 8 May 2018
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