Confrontation involves a hostile interaction between two opposing parties. Confrontation, in this situation, would not be a good idea. I don’t think you meant it in that way.
Perhaps what you are asking is whether or not you should approach her about your concerns. That might not be a good idea either because you and she are no longer friends. She may not welcome unsolicited advice about something so personal.
It might be a better idea to discuss your concerns with a school staff member or another trusted adult. This could be the guidance counselor, a teacher or the principal. If you choose not to, then your parents might be able to help.
It is good that you care about her well-being. The next step will be communicating your concerns to the right people, who will be able to help. Please take care.
Dr. Kristina Randle