Your wife seems to be paranoid and delusional. These are symptoms of psychosis. Your wife continues to believe in things that are not real despite evidence to the contrary. That is the definition of a delusion.
Psychosis is a break with reality. Psychosis is associated with several mental health disorders including bipolar disorder and schizophrenia. Sometimes people have episodes of psychosis that are not associated with the aforementioned disorders. Some people have one psychotic episode and never have another. If there are repeated psychotic episodes, then it might be indicative of a specific mental health disorder. Psychosis can be caused by mental illness, drug use, organic brain disorder, tumors, strokes, dementia, and alcohol and drug withdrawal.
What is causing her symptoms is not clear. Her current detoxification may be a contributor but a thorough evaluation is necessary to know for sure.
Report her symptoms immediately to her prescribing physician. It’s also important that she be evaluated by a medical professional. It might not be easy to convince her to have an evaluation but do your best.
Immediate intervention is necessary. Psychosis generally does not improve on its own. If necessary, take her to the hospital. Please take care.