ACS News Service Weekly PressPac -- Nov. 8, 2006



ACS News Service
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Here is the latest American Chemical Society (ACS) News Service Weekly press package (PressPac) with reports selected from 35 major peer-reviewed journals and Chemical & Engineering News.

In This Edition:

  • Squeezing more shelf life out of milk
  • Honey, I shrunk the carbon nanotubes!
  • Tripling the efficiency of a mainstay oil spill cleanup technology
  • Solving the structure of xDNA
  • Gene silencing technology is quietly moving toward the clinic
  • Journalists' Resources: Landmarks, news sources and more
  • Mark Your Calendars: Chemistry's growing role in cancer research

The information in this press package is intended for your personal use in news gathering and reporting and should not be distributed to others. Anyone using advance ACS News Service Weekly Press Package information for stocks or securities dealing may be guilty of insider trading under the federal Securities Exchange Act of 1934.

To download manuscripts and images, please click on the links provided with each item. Please cite the individual journal, or the American Chemical Society, as the source of this information.


ARTICLE #1 FOR IMMEDIATE RELEASE
Squeezing more shelf life out of milk
Journal of Agricultural and Food Chemistry

Putting the squeeze on milk may be a long-sought solution to the search for improved ways of killing harmful bacteria in milk and increasing its shelf life without introducing off-flavors into the beverage, researchers report.

Michael C. Qian and colleagues at Oregon State University point out that ultrahigh-temperature pasteurization (UHT) does produce milk that stays fresh at room temperature for six months. They add, however, that UHT leaves a "cooked" flavor in milk that has limited the popularity of UHT milk in the United States.

In experiments scheduled for publication in the Nov. 29 issue of the ACS biweekly Journal of Agricultural and Food Chemistry, they describe how a new food processing technology affects the taste of milk. Called high hydrostatic pressure processing (HPP), it involves putting foods under pressures that crush and kill bacteria while leaving food with a fresh, uncooked taste.

"Milk processed at a pressure of about 85,000 pounds per square inch for five minutes, and lower temperatures than used in commercial pasteurization, causes minimal production of chemical compounds responsible for the cooked flavor. HPP gives milk a shelf life at refrigerated temperature of at least 45 days," they note. ARTICLE #1 FOR IMMEDIATE RELEASE
"Effect of High-Pressure-Moderate-Temperature Processing on the Volatile Profile of Milk"

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http://pubs.acs.org/cgi-bin/sample.cgi/jafcau/asap/pdf/jf061497k.pdf
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CONTACT:
Michael C. Qian, Ph.D.
Oregon State University
Corvallis, Oregon
Phone: 541-737-9114
Fax: 541-737-1877
Email: michael.qian@oregonstate.edu


ARTICLE #2 FOR IMMEDIATE RELEASE
Honey, I shrunk the carbon nanotubes!
Nano Letters

Why would anyone want to shrink carbon nanotubes (CNTs), those cylinders of pure carbon with properties ideal for a new generation of sensors, transistors, super-strong fabrics, and nanoscale devices? CNTs already are about 50,000 times narrower than the finest human hair.

There are good reasons for doing so, according to Alex Zettl and colleagues at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory. They report development of a method for controllably altering the diameter of individual CNTs in the Dec. 13 issue of the ACS's Nano Letters. Zettl explains that CNTs' ability to conduct electricity and other electrical and mechanical properties depend heavily on their size. However, current methods for making CNTs cannot reliably control nanotube diameter, making it more difficult to fabricate devices from nanotubes.

"We have developed a method to shrink individual nanotubes to any desired diameter," the researchers report. "The process can be repeated in a highly controlled fashion, yielding a high-quality CNT of any preselected and precise diameter." The method involves a high-temperature that shrinks regular-sized CNTs and reforms them into high-quality tubes of a smaller diameter.

ARTICLE #2
"Shrinking a Carbon Nanotube"

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CONTACT:
Alex A. Zettl, Ph.D.
University of California, Berkeley, and
Lawrence Berkeley National Laboratory
Berkeley, California
Phone: 510-642-4939
Fax: 510-643-8793
Email: azettl@berkeley.edu


ARTICLE #3 FOR IMMEDIATE RELEASE
Tripling the efficiency of a mainstay oil spill cleanup technology
Environmental Science & Technology

Scientists in California report a major advance in the technology for cleaning up oil spills on oceans, lakes and other waterways. Victoria Broje and Arturo A. Keller describe construction and field tests of an improved version of the mechanical skimmer, the mainstay device for recovering oil spilled on water.

Relatively unchanged for decades, the typical skimmer consists of a revolving steamroller-like drum that picks up a film of oil on the drum's surface. A scraper then removes the oil, which drops into a collector. Broje and Keller note that traditional skimmers are inefficient, work poorly with thin oils like light crude or diesel and can be expensive to use in cleaning up large spills.

The new mechanical skimmer, described in a report scheduled for the Dec. 15 issue of the semi-monthly ACS journal Environmental Science & Technology uses a grooved surface. With a larger surface area, the grooves scoop up more oil than the smooth-surfaced traditional skimmer. The scraper is machined to precisely match the groove geometry, removing almost 100 percent of the adhered oil with each rotation. The grooves also are coated with an improved oil-adhering polymer. Field tests show that the new skimmer is up to three times more efficient than traditional skimmers, the scientists report.

ARTICLE #3 FOR IMMEDIATE RELEASE
Improved Mechanical Oil Spill Recovery Using an Optimized Geometry for the Skimmer Surface"

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CONTACT:
Arturo A. Keller, Ph.D.
University of California, Santa Barbara
Phone: 805-453-1822
Fax: 805-456-3807
Email: keller@bren.ucsb.edu


ARTICLE #4 FOR IMMEDIATE RELEASE
Solving the structure of xDNA
Journal of the American Chemical Society

James Watson and Francis Crick deciphered the structure of regular DNA 53 years ago. Now, scientists from Stanford University have determined the structure of xDNA. That's "expanded DNA," a strange double helix molecule that is 20 percent wider and more heat-resistant than natural DNA. Inherently fluorescent, expanded DNA glows in ways that may make xDNA useful as a medical and scientific probe.

Eric T. Kool and colleagues developed xDNA in 2003 by adding a benzene ring to the chemical bases that form natural DNA. Natural DNA, which is 20 angstroms wide, and benzene, with a girth of 2.4 angstroms, produced the wholly new wider double helix. The researchers now have combined all four expanded DNA bases with the four natural DNA bases to produce a complete eight-base molecule. They then used nuclear magnetic resonance to reveal the structure of xDNA and study the molecule.

In an article scheduled for publication Nov. 22 in the weekly Journal of the American Chemical Society, they describe the features needed for DNA that encodes and transfers genetic information. They report: "The present work shows that the eight-base xDNA system may have most if not all of these features, which suggests the future possibility of a functioning, replicable genetic system using xDNA as the genetic material."

ARTICLE #4
"Toward a Designed, Functioning Genetic System With Expanded-Size Base Pairs: Solution Structure of the Eight-Base xDNA Double Helix"

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CONTACT:
Eric T. Kool, Ph.D.
Stanford University
Stanford, California
Phone: 650-724-4741
Fax: 650-725-0259
Email: kool@stanford.edu


ARTICLE #5
EMBARGOED FOR RELEASE AT 9 A.M., EASTERN TIME, NOV. 13
Gene silencing technology is quietly moving toward the clinic
Chemical & Engineering News

The gene silencing technology showcased in the 2006 Nobel Prize in Physiology or Medicine is on an amazingly fast track toward use in treating a variety of serious diseases, according to an article scheduled for the Nov. 13 issue of the ACS's weekly newsmagazine, Chemical & Engineering News.

Much has happened to RNA interference (RNAi) technology in the eight years since discovery of this natural method for blocking the expression of specific genes, writes C&EN senior editor Celia Henry Arnaud. In addition to the Nobel Prize, RNAi-based treatments have gone into clinical trials for a common eye disease (age-related macular degeneration) and a viral infection of the lungs. Big pharma is confident that RNAi will find other uses, as evidenced by Merck's move in October to spend $1.1 billion in acquiring a company specializing in RNAi therapeutics.

The article explains that expanding the medical uses of RNAi depends on development of new systems for delivering so-called small interfering RNAs (siRNAs) to other parts of the body. Researchers are making progress on those delivery systems, with the first clinical trials of RNAi-packaged in delivery systems -- for cancer and hepatitis C -- possible in 2007.

ARTICLE #5
EMBARGOED FOR RELEASE AT 9 A.M., EASTERN TIME, NOV. 13
Delivering RNAi: Developing siRNA therapeutics depends on synthetic delivery systems

FOR FULL TEXT, CONTACT:
Michael Bernstein
ACS News Service
Phone: 202-872-6042
Fax: 202-872-4370
Email: m_bernstein@acs.org


Mark Your Calendars
Chemistry in Cancer Research: A Vital Partnership

Chemistry has an increasingly important role in research on cancer diagnosis, prevention and treatment. To spotlight that role, the American Chemical Society (ACS) and the American Association for Cancer Research (AACR) will cosponsor a special conference entitled, "Chemistry in Cancer Research: A Vital Partnership," Feb. 4-7 in San Diego, Calif. The program will feature presentations by prominent scientists on drug discovery, proteomics, the chemical biology of carcinogenesis, biomarkers and analytical chemistry, modeling and bioinformatics, and structural biology. (http://acswebcontent.acs.org/meetings/specialty/AACR/index.html)


Journalists' Resource: National Historic Chemical Landmarks

America came of age as a nation in the late 1700s -- the same time chemistry came of age as a science. Since then, chemists have played key roles in expanding the frontiers of knowledge, advancing medicine and industry, and creating products from aspirin to zippers. The ACS' National Historic Chemical Landmarks program recognizes these outstanding accomplishments and tells the stories behind the research. The most recent landmark was designated on Oct. 25, when ACS designated Procter & Gamble's development of Tide® -- "the washing miracle" synthetic detergent -- a National Historic Chemical Landmark in a special ceremony in Cincinnati, Ohio. The Landmarks' Web site click here has valuable resources for feature stories and background.


National Meeting Resources

A treasure trove of news sources, background material and story ideas is available from the ACS' latest National Meeting. Reporters can search and view abstracts of 10,000 scientific presentations, 600 non-technical summaries of those presentations and browse press releases online.

INDEX OF PRESS RELEASES
http://oasys.acs.org/acs/232nm/newsservice/tableofcontents.cgi?action=final

VIEW NON-TECHNICAL SUMMARIES
http://oasys.acs.org/acs/232nm/newsservice/viewpressrelease.cgi

GENERAL ACS NATIONAL MEETING INFORMATION
http://chemistry.org/meetings/sanfrancisco2006

ABSTRACTS FROM THE TECHNICAL PROGRAM
http://oasys2.confex.com/acs/232nm/techprogram/


ACS News Service Weblog Science, September & San Francisco

Visit the ACS News Service's National Meeting Weblog (http://acsnewsservice.typepad.com/sf_meeting/) for reports from scientific sessions and other events at the ACS National Meeting in San Francisco.

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ACS NEWS SERVICE
Weekly PressPac - Nov. 8, 2006
ALL CONTENT IS FOR IMMEDIATE USE EXCEPT ARTICLE #5 (EMBARGOED FOR 9 A.M., EASTERN TIME, NOV. 13, 2006)

PressPac Archive: http://www.chemistry.org/news/presspac.html

The American Chemical Society (ACS) News Service PressPac is your access point for discoveries in fields ranging from astronomy to zoology, which are reported in the 35 peer-reviewed journals of the American Chemical Society. With more than 158,000 members, ACS is the world's largest scientific society. Chemistry is the science that transforms lives, and these news alerts are from the leading edge of that science at ACS headquarters.

The American Chemical Society -- the world's largest scientific society -- is a nonprofit organization chartered by the U.S. Congress and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.


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