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Cost-effectiveness study of three antimalarial drug combinations in Tanzania

Researchers from the London School of Hygiene and Tropical Medicine have evaluated the cost-effectiveness of the three alternative combinations of drugs now recommended for the treatment of malaria in East Africa. They found that the drug combination that was the most expensive in the short term was in fact the most cost-effective, because its superior performance in curing malaria reduced the need for further treatment.

Resistance to malaria drugs is extremely common. The World Health Organization and other authorities now recommend the use of one of the new type of treatments (based on the Chinese drug artemisinin) combined with one of the older malaria drugs. It is thought that this combination approach will delay the appearance of artemisinin resistance. The combination of artemether and lumefantrine out-performed the other drug combinations in this research, which was conducted in Tanzania. The researchers say artemether and lumefantrine should be the preferred option in this part of Africa.

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Citation: Wiseman V, Kim M, Mutabingwa TK, Whitty CJM (2006) Cost-effectiveness study of three antimalarial drug combinations in Tanzania. PLoS Med 3(10): e373.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.doi.org/10.1371/journal.pmed.0030373

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-03-10-wiseman.pdf

CONTACTS:
Virginia Wiseman
London School of Hygiene and Tropical Medicine
Public Health and Policy
50 Bedford Square
London WCIB 3DP, United Kingdom
+44 207 299 4716
+44 207 299 4720 (fax)
virginia.wiseman@lshtm.ac.uk

About PLoS Medicine

PLoS Medicine is an open access, freely available international medical journal. It publishes original research that enhances our understanding of human health and disease, together with commentary and analysis of important global health issues. For more information, visit http://www.plosmedicine.org

About the Public Library of Science

The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org


Last reviewed: By John M. Grohol, Psy.D. on 21 Feb 2009
    Published on PsychCentral.com. All rights reserved.

 

 

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