Unlike other implants under development that apply an electric charge directly to retinal cells, the device does not cause the cells to heat up. It also uses very little power, so it does not need external batteries.
The retina, which lines the back and sides of the eyeball, contains photoreceptor cells that release signalling chemicals called neurotransmitters in response to light. The neurotransmitters pass into nerve cells on top of the photoreceptors, from where the signals are relayed to the brain via a series of electrical and chemical reactions. In people with retinal diseases such as age-related macular degeneration and retinitis pigmentosa, the photoreceptors become damaged, ultimately causing blindness.
Last year engineer Laxman Saggere of the University of Illinois at Chicago unveiled plans for an implant that would replace these damaged photoreceptors with a set of neurotransmitter pumps that respond to light. Now he has built a crucial component: a solar-powered actuator that flexes in response to the very low intensity light that strikes the retina. Multiple actuators on a single chip pick up the details of the image focused on the retina, allowing some "pixels" to be passed on to the brain.
The prototype actuator consists of a flexible silicon disc just 1.5 millimetres in diameter and 15 micrometres thick. When light hits a silicon solar cell next to the disc it produces a voltage. The solar cell is connected to a layer of piezoelectric material called lead zirconate titanate (PZT), which changes shape in response to the voltage, pushing down on the silicon disc. In future, a reservoir will sit underneath the disc, and this action will squeeze the neurotransmitters out onto retinal cells.
Author: Celeste Biever
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