Natural products discovery and production
New challenges, new opportunitiesNatural products have been the mainstay of the pharmaceutical industry. These compounds, as well as their semi-synthetic analogs and synthetic compounds based on the structure of natural products, have provided the most important antibiotics, antitumor agents, immunosuppressants, cholesterol-lowering agents, antiparasitic compounds and bioinsecticides.
This conference features talks and posters by the world leaders in natural products research. It examines how new natural products are discovered and modified, how their discoveries depend upon the study of uncultured microbes and on bioprospecting in new environmental sources such as the marine environment, how their production processes are improved by (i) genetics, (ii) scale-down procedures, (iii) metabolic engineering, and how they are reduced to practice by scale-up methods. Particular emphasis is placed on secondary metabolites such as inhibitors of fatty acid biosynthesis, biological control agents, antibacterial and antifungal antibiotics, antimalarials, alkaloids, enzyme inhibitors, immunosuppressants, hypocholesterolemic agents, flavonoids, carotenoids, and proteosome inhibitors.
Also included are products such as polysaccharides, vitamins, proteins and enzymes, and processes such as microbial cell culture, plant cell culture and algal fermentations. Lectures, posters, debates as well as panel discussions are featured. Many of the presentations emphasize new technologies to insure that natural product discovery continues to be a major force in the future of the pharmaceutical and other industries.
Last reviewed: By John M. Grohol, Psy.D. on 21 Feb 2009
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