PUMA protein coordinates the cell-suicide activities of p53 in the nucleus and cytoplasm

09/08/05

PUMA travels from the nucleus to the cytoplasm to free p53 from the grip of Bcl-xL, allowing p53 to trigger signaling on mitochondria that leads to cell death, according to St. Jude

Source: Eurekalert & others

Last reviewed: By John M. Grohol, Psy.D. on 21 Feb 2009
    Published on PsychCentral.com. All rights reserved.

 

 

The aim of psychoanalysis is to relieve people of their neurotic unhappiness so that they can be normally unhappy.
-- Sigmund Freud