PUMA protein coordinates the cell-suicide activities of p53 in the nucleus and cytoplasm

09/08/05

PUMA travels from the nucleus to the cytoplasm to free p53 from the grip of Bcl-xL, allowing p53 to trigger signaling on mitochondria that leads to cell death, according to St. Jude

Source: Eurekalert & others

Last reviewed: By John M. Grohol, Psy.D. on 21 Feb 2009
    Published on PsychCentral.com. All rights reserved.

 

 

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