Lowell receives Smith Family Award for Excellence in Medical Resarch
BOSTON – Bradford B. Lowell, MD, PhD, an investigator in the Division of Endocrinology at Beth Israel Deaconess Medical Center (BIDMC) has received the Smith Family Award for Excellence in Medical Research from the Richard and Susan Smith Family Foundation.
The award, which was created in 2002 to recognize unique, outstanding contributions among particular scientific disciplines, is periodically made to a former recipient of the Smith Family New Investigator Awards Program, which supports newly appointed junior faculty engaged in innovative basic research in the areas of AIDS, cancer, cardiovascular disease, diabetes or neuroscience.
Honored as a Smith Family New Investigator in 1994 for his work in diabetes and obesity research, Lowell is the fourth recipient of the foundation's Award for Excellence in Medical Research, for which he received a $65,000 cash prize at a scientific meeting held May 24.
"The New Investigator Awards Program was created because we wanted to ensure that our support of medical research would make a difference," says Richard A. Smith, co-chair of the Richard and Susan Smith Family Foundation.
Lowell's investigations utilize genetically engineered mice to probe the cellular and molecular mechanisms responsible for obesity and its complications. These studies have led to important discoveries regarding the means by which the brain controls fat stores.
Among other findings, Lowell's lab has discovered an important role for uncoupling protein-2 in causing obesity-induced loss of pancreatic beta-cell function in type 2 diabetes. He has also identified molecular pathways mediating diet-induced thermogenesis and established the importance of beta-adrenergic receptors in regulating energy expenditure. His laboratory is also in the process of conducting neuroanatomical mapping studies to identify neurocircuits that may be important in regulating food intake and energy expenditure.
An associate professor of medicine at Harvard Medical School, Lowell received both his medical degree and a doctoral degree in physiology from Boston University School of Medicine. He went on to complete his residency in internal medicine and a fellowship in endocrinology, both at the former Beth Israel Hospital. He is Director of the Beth Israel Deaconess Medical Center Transgenic Program.
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