New drug-resistant strain of salmonella identified
NB. Please note that if you are outside North America, the embargo for LANCET press material is 0001 hours UK Time 16 April 2004.
Researchers from Taiwan report the identification of a new form of drug-resistant salmonella bacterium in this week's issue of THE LANCET.
Salmonella enterica serotype choleraesuis usually causes infections that require antimicrobial treatment. Multidrug-resistant strains have been identified, but the antimicrobial ceftriaxone has been effective against them so far.
Professor J T Ou, from Chang Gung University College of Medicine, Taoyuan, Taiwan, and colleagues isolated a strain of Salmonella enterica serotype choleraesuis that was resistant to all antimicrobials commonly used to treat salmonellosis, including ceftriaxone and ciprofloxacin. The bacterium came from a 58-year-old man with sepsis who subsequently died.
The drug-resistance was due to changes in the genes of the bacteria, including some in a genetic element that can potentially be transmitted between bacteria. Although this strain was from only one patient, the public-health implications of multidrug-resistant salmonella are serious. "Constant surveillance is needed to prevent its further spread," warn the authors.
Source: Eurekalert & othersLast reviewed: By John M. Grohol, Psy.D. on 21 Feb 2009
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