Diagnosis of Schizophrenia Ups Risk of Suicide Attempts

University of Toronto researchers have discovered that among individuals with schizophrenia, the risk of suicide attempts is significantly elevated.

Sadly, investigators found that those with schizophrenia who’d been physically abused during childhood were five times more likely to have attempted suicide.

Overall, the lifetime prevalence of suicide attempts among individuals with schizophrenia was 39.2 percent compared to 2.8 percent of those without the disorder, according to the study.

“Even after taking into account most of the known risk factors for suicide attempts, those with schizophrenia had six times the odds of having attempted suicide in comparison to those without schizophrenia,” reported lead author Dr. Esme Fuller-Thomson.

The study examined a representative sample of 21,744 community-dwelling Canadians, of whom 101 reported they had been diagnosed with schizophrenia. Data were drawn from the 2012 Canadian Community Health Survey-Mental Health.

“When we focused only on the 101 individuals with schizophrenia, we found that women and those with a history of drug or alcohol abuse and/or major depressive disorder were much more likely to have attempted suicide,” said co-author Bailey Hollister, a recent social work graduate.

Traumatic events in youth appear to be a strong influence for suicidal ideation. Researchers discovered individuals with schizophrenia who reported that they had been physically abused during their childhood were five times more likely to have attempted suicide.

Statistically, this history of abuse and other early adversities explained 24 percent of the variability in suicide attempts, said the authors.

“Clearly those with schizophrenia are an extremely vulnerable population. Knowledge of the added risk of suicide attempts associated with childhood abuse and substance abuse could help clinicians improve targeting and outreach to this population,” said Fuller-Thomson.

Source: University of Toronto
 
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