A new analysis of birth and hospital records shows that parents with autistic children were roughly twice as likely to have been hospitalized for a mental disorder than parents with children who were not autistic.
The researchers examined 1,237 Swedish children born between 1977 and 2003 who were diagnosed with autism before age 10, and compared them with 30,925 control subjects matched for gender, year of birth and hospital.
The link between autism and a parent’s hospitalization for a mental disorder, such as depression or schizophrenia, was present regardless of the timing of the parent’s diagnosis relative to the child’s diagnosis.
“We are trying to determine whether autism is more common among families with other psychiatric disorders. Establishing an association between autism and other psychiatric disorders might enable future investigators to better focus on genetic and environmental factors that might be shared among these disorders,” said study author Julie Daniels, Ph.D., an assistant professor in the UNC School of Public Health’s epidemiology and maternal and child health departments.
“Earlier studies have shown a higher rate of psychiatric disorders in families of autistic children than in the general population,” she said. “We wanted to see if the parents of autistic children were more likely to be diagnosed with mental disorders.
The large sample size in the study also enabled researchers to distinguish between psychiatric histories of mothers versus fathers in relation to autism.
“Our research shows that mothers and fathers diagnosed with schizophrenia were about twice as likely to have a child diagnosed with autism. We also saw higher rates of depression and personality disorders among mothers, but not fathers,” Daniels said.
This information will help researchers look among related diseases, such as psychiatric disorders, for causes of autism, Daniels said. “It may eventually help identify opportunities to prevent or treat the disorder.”
The study appears in the May 2008 issue of the journal Pediatrics.