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Trazodone (Desyrel)
Overall Rating
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6.73
Rating:

6.73

Side Effects
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5.33
Pricing
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7.25
Average Price: $17.00 Thumbs up Recommended By
80% of reviewers (of 15 reviews)
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Trazodone

Generic Name: Trazodone TRAZ-oh-done

Drug Class: Antidepressants, miscellaneous

 

Contents

 

Description
This medicine is used for treatment of depression. Your doctor may have prescribed this medicine to help relieve, anxiety, tension or to help you sleep. Your doctor may have prescribed this medicine for other conditions as well.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Follow the directions given to by your doctor. This medicine should be taken orally on a regular basis. It is best that that you take this medicine at bedtime unless otherwise directed by your doctor. The extended-release tablet and capsule should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or capsule.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • dizziness, drowsiness
    • agitation, confusion
    • Consult your doctor immediately if you experience prolonged and painful erections.
    • Expected side effects are increased appetite and weight gain.
    • drowsiness, fatigue, dizziness
    • dry mouth
    • Unreported side effects are possible, talk to your healthcare provider if any other symptoms occur.
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Warnings/Precautions
    • Do NOT stop taking this medicine abruptly.
    • This medicine may cause dizziness or drowsiness.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • Don't drive or perform other tasks that require concentration, until you know how this medicine affects you.
    • This medicine can increase the risk of suicidal thinking and behavior in some children and teens. Parents of children taking antidepressants should watch for signs of worsening depression or unusual changes in behavior.
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Overdose
Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Before taking any new prescription or over-the-counter medication, talk to your doctor or pharmacist.
      Taking this medicine together with diazepam (Valium) may impair movement ability.
      Avoid using this medicine with MAO inhibitors. Your doctor or pharmacist can tell you if you are taking an MAO inhibitor.
    • Talk to your doctor if you are taking certain antibiotics such as erythromycin, clarithromycin or azithromycin. This medicine should not be taken with MAO inhibitors.
    • Let your doctor know if you are taking any vitamin supplements or herbal products. St. John’s Wort should be avoided while taking fluvoxamine due to the increased side effects of too much serotonin.
    • MAO inhibitors should not be taken while taking the following drugs:
      • dexfenfluramine
      • fluoxetine (Prozac)
      • fluvoxamine (Luvox)
      • paroxetine (Paxil)
      • sertraline (Zoloft)
      • venlafaxine (Effexor
      • Effexor XR)
    • Tell your doctor if you are taking other antidepressants, medications for blood pressure, medications for diabetes, sleeping pills, tranquilizers, vitamins or herbs.
    • This medicine may increase the affects antihypertensive drugs, drugs with sedative effects, phenytoin (Dilantin) or fosphenytoin (Celebyx) and tramadol (Ultram).
    • Do not take MAO inhibitors type A with this medicine. If you are not sure if you are taking an MAO inhibitor, talk to your doctor or pharmacist. Certain other antidepressants, clozapine (Clozaril), haloperidol (Haldol), lithium, trazadone, and others may increase the risk of seizures. BEFORE taking any new prescription or over-the-counter medicine, talk to your health care provider.
    • Patients taking MAO inhibitors should not be take this medicine.
    • Nafazodone can decrease the effects of clonidine, methyldopa, diuretics (water pills), warfarin and drugs used to lower blood sugar (hypoglycemics). This medicine can increase the toxic effects of; terfenadine, astemizole, fluoxetine (Prozac), triazolam, alprazolam (Xanax) and phenytoin (Dilantin). Do not take this medicine within 14 days of stopping MAO inhibitors. If you are not sure what an MAO inhibitor is, talk to your doctor or pharmacist. If you are currently taking any of these medicines, talk to your doctor or pharmacist to see if Nefazodone is right for you.
    • Possible drug interactions may occur with phenobarbital causing a decrease in the effect of the medications. Severe blood pressure problems and seizure can occur with taken with MAO inhibitors.
    • Talk with your physician or pharmacist if you are taking other medications.

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Pregnancy/Nursing
If you are pregnant or thinking of becoming pregnant, before taking this medicine talk to your doctor about the benefits versus the risks to your pregnancy.
In testing with animals, studies show delayed bone development. Use this medicine only if it clearly necessary. It is advised not to take this medicine while nursing. If you have any concerns, talk to your doctor or pharmacist.

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More Information

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other benefits. However, studies have shown that a small number of people (especially children/teenages) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with a doctor about the risks and benefits of antidepressant medication, even if the treatment is not for a mental condition. Tell your doctor immediatley if you notice worsening depression, unusual behavior changes, (including possible suicidal thoughts/attempts), or other mental/mood changes. Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.
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Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.



Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.





 

desyrel1

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DaveyJones
Grand Member


Registered: September 2005
Posts: 884
Review Date: Fri September 8, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): Works well for sleep, inexpensive
Negative aspects of this (cons): Takes a while to get used to

I was prescribed this medicine to help me sleep a number of years ago. It works very well for me used in this way, I sleep 7 - 8 hours a night. When I first started taking it, however, I felt intoxicated when I awoke. This went away after a week or two. I tolerated it because I was finally getting rest again.
MyBestKids2
Grand Magnate

Registered: September 2006
Posts: 4897
Review Date: Mon September 11, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): encourages sleep
Negative aspects of this (cons): makes me too sleepey

Trazadone should be a last resort for patients who have had an ongong sleep disturbance.
DizzyLizzy
Member


Registered: August 2006
Posts: 20
Review Date: Mon September 11, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 9 

 
Positive aspects of this (pros): works very well
Negative aspects of this (cons):

I have been using Trazodone for over 5 years. I take it at bedtime to help me stay asleep, and the doctor prescribed it as a sleep medication... however, it has also helped by keeping my mild depression away. Other anti-depressants were always too strong for my mild depression, but Trazodone has worked great for the mild depression and as an aid to help me sleep.
eskielover
Magnate


Registered: October 2004
Posts: 2487
Review Date: Thu September 14, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 4 

 
Positive aspects of this (pros):
Negative aspects of this (cons): extream sleepiness, dizzyness, along with migraine pain

Trazadone also known as desyrel, had the same effects. The worse part was the dizziness caused by an extreme drop in blood pressure. Along with that came sleepiness & migraine headache pain. The blood pressure drop was the most serious part of taking the med & taking it was immediately stopped.
Rainbowzz
Grand Magnate


Registered: December 2005
Posts: 4278
Review Date: Thu September 14, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 3 

 
Positive aspects of this (pros): lightened anxiety by a small amount
Negative aspects of this (cons): did not make me sleepy -at- all.

Was prescribed for both sleep disorder and bipolar. Had a nice lightening of anxiety the next morning, but did not help me to sleep at all even with higher doses.
Amerikasend
Member

Registered: December 2006
Posts: 28
Review Date: Mon December 4, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 1 

 
Positive aspects of this (pros): none
Negative aspects of this (cons): gave me a stuffy nose and a headache

I was prescribed this for sleep. Didn't help me sleep at all, but it did give me a real bad stuffy nose and a headache. I threw this crap in the garbage.
bandia
Junior Member


Registered: June 2006
Posts: 10
Review Date: Fri December 8, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): i fall asleep within minutes and stay asleep
Negative aspects of this (cons): it lowers my blood pressure

After trying every sleep med known to humankind, Traz hit the spot. It did lower my blood pressure & I briefly went off it & back on Lunesta. Bye-bye sleep! I decided to take the side effect (I sometimes feel "swimmy" & when I do, I just pause and let my heartbeat settle) without hesitation when the docs said it was ok to take Traz if I wanted. I only need to take 12.5 mg a night.
Review Date: Thu December 28, 2006 Would you recommend this? Yes | Total Spent: $30.00| Rating: 7 

 
Positive aspects of this (pros): works good for sleep...
Negative aspects of this (cons): ...only if taken with Ambien CR

see my review under Ambien CR.... it worked wonders for helping me sleep as long as I took it with Ambien CR
Grace03
Member


Registered: March 2007
Posts: 45
Review Date: Thu March 22, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): Seems to control "racing thoughts" associated with Bipolar II. Allows the thoughts to slow down, so I can sleep. Combined with Seroquel=good sleeping meds
Negative aspects of this (cons): Drowsiness: take at bedtime

;
DoubtingThomasina
Junior Member


Registered: April 2007
Posts: 19
Review Date: Wed April 11, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 10 

 
Positive aspects of this (pros): works wonders for insomniacs!
Negative aspects of this (cons): a little groggy in am

Trazodone is excellent for insomniacs. Knocks you out in 20 minutes or less. Hard to wake in the am but once you do, you feel well rested. It also works will with other antidepressants like Zoloft. Watch out for mild mania. Mood stabilizers necessary for Bipolaroids taking Trazodone.
mrstumnus
Member


Registered: April 2007
Posts: 23
Review Date: Thu April 26, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 7 

 
Positive aspects of this (pros): Great for sleep, good for anxiety and mood.
Negative aspects of this (cons): Dizziness (short-lived), nasal congestion, water retention.

I found Trazodone helped me sleep tremendously. It did make me feel very dizzy and slightly disorientated but this wears off after about 45 mins. It also causes a rather unpleasant nasal 'blocked' feeling, this is bearable though. It is very good for anxiety, I felt quite 'chilled' and calm, my mood felt considerably better though in a relaxed state, no 'hyper' feeling. Maybe best for short-term sleeping problems or extreme anxiety. No sexual side effects (female), slightly increased appetite and minor weight gain (but this was only due to fluid retention). Some 'hangover' tiredness next day. I assume this would lessen with further use.
cherryblossom
Member


Registered: April 2007
Posts: 24
Review Date: Sat May 12, 2007 Would you recommend this? Yes | Total Spent: $4.00| Rating: 10 

 
Positive aspects of this (pros): helps me sleep
Negative aspects of this (cons): don't know of any

this medicine works good with my other meds.I get so sleepy in about 30 min after I take it.
Prada
Member

Registered: August 2007
Posts: 33
Review Date: Fri September 14, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 7 

 
Positive aspects of this (pros): helped with sleep
Negative aspects of this (cons): headaches, nausea, dizziness

It worked well, but the side effects were horrible. The 'hangover' feeling was worse than if I were to drink myself to alcohol poisoning.
clskrock
Member


Registered: February 2008
Posts: 45
Review Date: Fri February 15, 2008 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 6 

 
Positive aspects of this (pros): Makes me drowsy.
Negative aspects of this (cons): nausea

My dosage was just increased to 150mg. which has upset my stomach.
missnsx
Visitor

Registered: February 2008
Posts: 2
Review Date: Thu February 28, 2008 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): Definately helped me fall asleep
Negative aspects of this (cons): Crazy dreams!!

I found that it really helped me fall asleep quickly and stay asleep throughout the night. Lunesta and Ambien do not work for me however Trazodone does the trick. The only downside is that it causes me to have very strange and crazy dreams. Some of my friends whom have also taken it have also noted that it caused them to have weird dreams too.