These are the top 20 psychiatric medications by number of U.S. prescriptions dispensed in 2005.

  MedicationUsed for…U.S. Prescriptions
1. Xanax Anxiety 34,230,000
2. Zoloft Depression, anxiety 26,976,000
3. Lexapro Depression, anxiety 24,788,000
4. Prozac Depression, anxiety 21,403,000
5. Ativan Anxiety, panic disorder 19,002,000
6. Effexor XR Depression, anxiety 17,179,000
7. Klonopin Anxiety 16,763,000
8. Elavil Depression, migraines 14,385,000
9. Valium Anxiety, panic disorder 12,093,000
10. Wellbutrin XL Depression 11,044,000
11. Celexa Depression, anxiety 9,266,000
12. Adderall XR Attention deficit disorder 8,653,000
13. Seroquel Antipsychotic, behavioral problems 8,420,000
14. Risperdal Antipsychotic 7,301,000
15. Strattera Attention deficit disorder 4,991,000
16. Cymbalta Depression, diabetes 4,938,000
17. Zyprexa Antipsychotic, behavioral problems 4,540,000
18. Depakote Bipolar, migraines 4,077,000
19. Buspar Sleep, anxiety 4,054,000
20. Paxil Depression, anxiety 3,609,000