Psych Central

Clinical Trials Library


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Light Therapy for Bipolar Disorder

July 25th, 2013
Light therapy for seasonal affective disorder (SAD) has been studied for some time now. Usually it comes to mind with the onset of depression in winter. But more applications have been coming to the forefront. Recently, a post on Psych Central had information ...

Art Therapy: Beneficial Schizophrenia Treatment?

Art Therapy: Beneficial Schizophrenia Treatment?Recent findings question the popular use of art therapy for people with schizophrenia. Schizophrenia affects up to one in a hundred people at some point and can cause hallucinations, delusions, and loss of energy and motivation. Creative psychological interventions such as art ...

The Lab Rat Chronicles: A Neuroscientist Reveals Life Lessons from the Planet’s Most Successful Mammals

BOOK REVIEW.
Kelly Lambert, PhD is undoubtedly in the right field. She has a passion for the laboratory and a knack for applying its lessons to daily life. The Lab Rat Chronicles: A Neuroscientist Reveals Life Lessons from the Planet’s Most Successful Mammals is a thoughtful, fact-filled treat for the intellectual (but not necessarily scientific) mind. ...

Music Therapy May Aid Brain-Damaged Patients

Music Therapy May Aid Brain-Damaged PatientsA review of the evidence to date suggests that music therapy can help patients recover their movements after experiencing brain damage. Brain damage can affect movement and language abilities, having a significant impact on quality of life. Patients may have had ...

Higher Risk of Mental Health Problems for Homosexuals

Homosexual people tend to experience more mental health problems than heterosexual people, research indicates. Discrimination may contribute to the higher risk, believes lead researcher Dr. Apu Chakraborty of University College London, UK. His team looked at rates of mental disorder among 7,403 adults living in the UK, whose details were obtained from the Adult Psychiatric Morbidity ...

Depression: New Medications On The Horizon

Depression: New Medications On The Horizon With the advent of monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs) in the 1950s, depression treatment was revolutionized. These medicines target the monoamine system, including the neurotransmitters serotonin, norepinephrine and dopamine. For decades, the ...

Depression’s Links to Heart Disease

Persistent depressive symptoms are common after angina, heart attack, or other heart problems. Depressive symptoms also are thought to increase the risk of further heart problems and mortality. Dr. Michael Rapp from St. Hedwig's Hospital, Berlin, and his team enrolled 22 patients three months after hospitalization for acute coronary syndrome. The patients had brain scans to highlight ...

Homeopathy: Less Is More

Samuel Hahnemann, a German physician, developed homeopathy in the late eighteenth century. He did so because of his dissatisfaction with the conventional medicine of his time. Hahnemann suggested two key principles. First, he asserted that “like cures like.” In other words, a substance that produces certain symptoms in a healthy person can be used to ...

Heart, Blood Pressure Medications and Dementia

Heart, Blood Pressure Medications and Dementiaheart and blood pressure medications reduce dementia risk? Drugs for high blood pressure and heart disease have been linked to protection from Alzheimer's disease and dementia. A team led by Professor Benjamin Wolozin of Boston University looked at the possible effects of angiotensin receptor ...

Research 101: Understanding Research Studies

One of the secrets of science is to understand the language of science, and science's primary language is the research study. Research studies allow scientists to communicate with one another and share results of their work. There are many different kinds of research and many varying fields of research. And although journals were designed to ...

Good Reasons To Keep Taking Your Medication

Many research studies have highlighted the phenomenon of the "healthy adherer" — people who take their medications consistently demonstrate more healthy behavior overall. Backing up this idea are studies showing better outcomes for patients who consistently take their pills, even when those pills are a placebo. The patients' feeling of being cared for and caring

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Checklist of Questions for Clinical Trial Participants

So you have been asked to take part in a research study! This can be a very satisfying experience, allowing you to help yourself now and to help others in the future. After all, without research, treatment cannot improve, and without those who take part, there would be no research! You are the one who ...

Learning About the Results of Research

In most informed consent forms, the researcher promises to share what is learned from the study with you. These results will sum up the responses of everyone who took part in the study. In addition, the researcher will discuss with you any results that relate to your diagnosis or that may be useful in deciding ...

Will You Have Access to Those Drugs That Work After a Trial Is Complete?

Understandably, if an investigational drug helps you, you may wish to continue to take it after the trial has been completed. In some instances, a medication that is being investigated for use in treating your illness may have been approved by the Food and Drug Administration (FDA) for other uses. If you find that you ...

Involvement of Family Members and Others

You may wish to involve family members in some parts of a research study. For example, you might consult with a family member about taking part in the study, or you may wish to look over this booklet with a family member or close friend and discuss being a research subject with that person. If ...

What Is Informed Consent?

Federal regulations have been created to protect the well-being and rights of volunteers in biomedical research. These regulations (Title 45 Code of Federal Regulations Part 46 or 45 CFR 46) say no investigator may involve anyone as a subject in research without getting that person's informed consent, either directly or from the person's legal representative. A ...

Does Research Involve Special Risk?

Well before a clinical study begins, the researcher has attempted to reduce any risk of physical discomfort or harm to you and others who take part. The effort likely began with preclinical, or basic, laboratory research that probably included animal studies, for example, to test the safety of a new drug. Yet, for research to ...

What Protections Exist for Research Subjects?

Many "checkpoints" ensure that research meets strict scientific guidelines and follows rules that protect the subject. Several groups who are not part of the research team examine both the scientific plan and procedures to protect the interests of participants before an investigator may begin the research. Each proposed study, including its provisions for the protection of ...

What Is the Investigator’s Responsibility if a Patient Has a Clinical Crisis?

You read earlier about the differences between clinical research and the care you receive from your personal doctor. In most research, an investigator will try to follow the research design: Following a research plan that has met all of the conditions described in the next section of this pamphlet conditions meant to ensure that any ...

What Is a “Placebo Control” in a Medication Trial?

Studies of new drugs often compare the effects of an investigational drug with the effects of a placebo. If you are considering whether to take part in a drug trial, the director of the study must tell you if the study will use a placebo control. The informed consent form that you will sign if ...

How Are Clinical Studies of Mental Disorders Designed?

Clinical researchers call the standard scientific approach for trying out treatments a double-blind, randomized, controlled clinical trial. Understanding this term, and knowing how and why this approach is used, should help you to decide whether to become a research volunteer. An important part of scientific research is comparison. Clinical research often will compare an investigational treatment ...

How Will Treatment in a Clinical Research Study Differ from Treatment Your Own Doctor Provides?

Clinical research often involves providing treatment. Yet, treatment research is different from the care that you would get from your own doctor. Usually, when you go to a doctor, you want help with a particular problem. You count on your doctor to do what is best for you. You know that anything your doctor suggests ...

What Is Mental Health Clinical Research?

Scientists study and try different ways to diagnose, treat, and prevent human disease more effectively. The needed research may take place in a basic science laboratory, a clinic, or in the community. In mental health clinical research, the term "clinical" means that the research involves persons in actual patient care settings. These may be inpatient settings ...