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Generic Name: Pemoline (PEM-oh-leen)

Drug Class: Stimulant


Cylert (Pemoline) is a stimulant medication that is used to treat attention-deficit hyperactivity disorder (ADHD) in children, as well as in the treatment of narcolepsy.

As of March 2005, Cylert has been discontinued for sale and manufacture in the United States and is no longer available.

Pemoline is similar to amphetamines or Ritalin. The exact way pemoline alters behavior in children is not known. Pemoline works in the brain and has been shown to decrease fatigue, increase alertness, and increase mood.

This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.

How to Take It

Pemoline comes as a tablet and is usually taken once a day. Taking this medicine in the morning is recommended to avoid trouble sleeping at night. Your child should take this medicine exactly as directed. Your child should not take more or less than prescribed by your doctor. Continue to give this medicine to your child even if your child is feeling better. Do not stop this medicine, until you have spoken with your doctor. This medication comes with a consent form. Make sure to read and sign the consent form before your child begins taking pemoline.

Side Effects

Side effects that may occur while taking this medicine include:

  • weight loss / loss of appetite
  • trouble sleeping
  • drowsiness
  • lightheadedness
  • dizziness
  • headaches

Contact your doctor immediately if your child experiences:

  • shortness of breath / breathing trouble
  • unusual tiredness
  • nausea and vomiting
  • skin rash
  • fast heartbeat
  • swollen or painful glands
  • unusual bleeding or bruising
  • Convulsions (seizures)
  • large pupils
  • sores, ulcers, or white spots on lips or in mouth

Warnings & Precautions

  • Pemoline can cause serious and sometimes deadly liver damage in children.
  • Your child may experience loss of appetite
  • Your child may experience excessive tiredness
  • Your child may experience lack of energy
  • Your child may experience upset stomach
  • Your child may experience dark urine
  • Your child may experience yellowing of the skin or eyes
  • For an overdose, seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

Drug Interactions

Before taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. This includes supplements and herbal products.

Dosage & Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses or take extra medicine to make up for the missed dose.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (preferably not in the bathroom). Throw away any medication that is outdated or no longer needed.


If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is NOT known if this medicine is excreted in breast milk. It is recommended that you DO NOT breast-feed while taking this medicine unless your doctor or pediatrician has told you to.

More Information

For more information, talk to your doctor, pharmacist or health care provider, or you can visit this website, for additional information from the manufacturer of this drug.



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One thought on “Cylert

  • March 16, 2020 at 4:50 pm

    I was on this drug for 4 years and to this day I have been paying for a drug that was not properly tested.


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APA Reference
Psych Central. (2018). Cylert. Psych Central. Retrieved on October 26, 2020, from


Scientifically Reviewed
Last updated: 8 Oct 2018
Last reviewed: By Christine Traxler, M.D.
Published on All rights reserved.