DBS for Depression: Still Mixed ResultsDeep brain stimulation (DBS) is a treatment long used for Parkinson’s disease. But in the past decade, some researchers have also examined its use for the treatment of severe clinical depression.

Severe major depression is a serious problem in society, because some studies estimate that up to 30 percent of those who attempt to be treated for it find they have “treatment resistant” depression — that is, traditional treatments simply don’t work very well.

Deep brain stimulation has mixed results. As we reported on back in February, a long-term followup of 20 patients found an average response rate to DBS of 64 percent. Not shabby, but also not the hopeful, guaranteed cure it was once held out to be.

Maiken Scott, the behavioral health reporter for Philadelphia station WHYY, has a story following a handful of patients in a local clinical trial looking into the effectiveness of DBS for depression.

2 Comments to
DBS for Depression: Still Mixed Results

Before posting, please read our blog moderation guidelines. The comments below begin with the oldest comments first. Click on the last comments page to jump to the most recent comments.

  1. John – Thanks for this article. I wonder what type of patient responds to RTMS and its success rate.

  2. My sister had DBS for depression almost 2 years ago. Right after surgery she suffered 4 grand mal seizures. She was not responsive for 2 days. She finally woke up. She was like a 54 year old toddler. She was an intelligent person before DBS. She now has memory problems, lacks problem solving skills, has erratic, impulsive behavior, exhibits immaturity, and suffers from colitis along with many other new physical ailments. The depression is still there. One and a half pages of medications continue to be used. The sister that I knew has basically been replaced by a needy, confused person. The DBS study calls her a success. Funny,huh?

Join the Conversation!

Before posting, please read our blog moderation guidelines.

Post a Comment:

(Required, will be published)

(Required, but will not be published)


Recent Comments
  • Sybille Stahl: The difference between me telling my children that Santa Claus is real and telling them that Jesus is...
  • Tara: “Love and intimacy don’t blossom by trying to pull it toward us or manipulating people. ”...
  • Emma: What a tragic loss of such an amazing soul. I wonder what would have made the difference for him between life...
  • Lilly: Jane, you realize that the genetic markers for schizophrenia were only found this year, right? Before that...
  • owl: Mid life crises.
Subscribe to Our Weekly Newsletter

Find a Therapist
Enter ZIP or postal code

Users Online: 9645
Join Us Now!