Antidepressant Articles

Research Suggests Pregnant Women Forgo Antidepressants, With One Exception

Monday, November 5th, 2012

Research Suggests Pregnant Women Forgo Antidepressants, With One ExceptionConventional wisdom has been for women who are taking antidepressant medication, to stay on it even while pregnant. Try to discontinue such medications can often be a long, slow process that has its own ups and downs. (Ask anyone who’s ever been on antidepressant for a year or more — it’s not fun trying to get off of it.)

It turns out, though, that conventional wisdom is largely wrong. Most infertile women who are taking popular antidepressants — such as Prozac, Paxil or Celexa — would help their unborn child by discontinuing the medication. With one exception — those women who are suffering from a severe depression (versus mild or moderate depression).

Why? Those women taking antidepressants nearly double the risk of a miscarriage if they stay on them during their pregnancy.

Budeprion XL 300, Generic Wellbutrin, To Be Withdrawn

Friday, October 5th, 2012

Budeprion XL 300, Generic Wellbutrin, To Be WithdrawnIn 2007, The People’s Pharmacy, a newspaper drug advice column by Joe and Terry Graedon, noted on their website that they started getting reports from people taking a generic form of Wellbutrin called Budeprion XL 300 mg. These reports discussed how patients taking the generic version of this antidepressant weren’t experiencing the same beneficial effects of the medication as when they were taking the name-brand version. And the side effects were often worse.

The Graedons became so concerned that they commissioned an independent lab analysis of the generic version of Wellbutrin manufactured by Impax Lab and Teva Pharmaceuticals in 2007. This report found that the generic version of Wellbutrin simply wasn’t equivalent to the brand-name version.

In April 2008, the FDA reviewed their existing studies, and concluded they were the same. The FDA did not review the independent analysis, or any actual data on the 300 mg version of the product (you know, the one people were actually complaining about).

Here it is more than four years later, and the U.S. Food and Drug Administration (FDA) finally agrees with the independent analysis, the Graedons, and the hundreds of people who’ve complained about the efficacy of Budeprion XL.

4 Tips for Caring for Yourself After a Depressive Episode

Tuesday, July 10th, 2012

4 Tips for Caring for Yourself After a Depressive Episode Experiencing one depressive episode increases your risk for experiencing another. So in order to reduce the risk, it’s important to be proactive and take good care of yourself.

In his new book, Depression: A Guide for the Newly Diagnosed, clinical psychologist Lee Coleman, Ph.D, ABPP, includes a valuable chapter on how to take care of yourself after a depressive episode. Coleman also serves as the assistant director and director of training at the California Institute of Technology’s student counseling center.

Below you’ll find four helpful tips for caring for yourself after an episode of depression.

What Club Drug May Help Depression?

Monday, July 9th, 2012

What Club Drug May Help Depression?Antidepressants not working for you? Psychotherapy a drag? Supplements no better than a sugar pill?

You might want to check out a drug more popularly known among the club scene and all-night dance parties than for the treatment of depression.

As we reported last month, researchers are taking a second look at ketamine — also known as Special K in the club scene — to help with depression.1 It appears it has the potential to be faster-acting than traditional antidepressants, which may make it a new treatment option for people who are depressed and are suicidal or in crisis.

Ketamine is already approved for certain medical uses, such as a human anesthetic, but its use is tightly controlled by the U.S. Drug Enforcement Administration because of its potential for abuse. Now a number of pharmaceutical companies are investigating its use in the treatment of depression with active research trials around the world.

Footnotes:

  1. We also noted nearly 2 years ago that ketamine also provides relief to bipolar patients. []

Top 5 & 25 Psychiatric Medications for 2011

Wednesday, June 13th, 2012

Top 5 & 25 Psychiatric Medications for 2011

Medications used to treat mental disorders continue to enjoy the best sales they’ve had ever. Meanwhile, psychotherapy usage continues to decline.

We started tracking the top 25 psychiatric medications prescribed in the U.S. back in 2005, with the help of IMS Health and their innovative Xponent service, which tracks the vast majority of prescriptions dispensed in the U.S.

The top 5 are below, while the rest of the list follows.

Video: 6 Ways to Prepare for Antidepressant Withdrawal

Saturday, May 26th, 2012

[caption id=”attachment_4049″ align=”alignleft” width=”225″ caption=”A row of split and shaved Paxil fragments, lined up in descending size, that I took near the end of my …

Video: Anxious? You’re Not Alone: Check Out These Anxiety Blogs

Saturday, May 12th, 2012

I am not the only person with an anxiety disorder.

Likewise, you are not the only person with an anxiety disorder.

But it can sure feel that way sometimes, eh? Especially on days when everyone else at the party is acting super sociable, but you’re slunked (is that a word?) down in a corner and too dizzy to talk to anyone.

It’s easy to feel alone on days when everyone else seems to be gathering their groceries from the store shelves just fine, but you’re still hovering in the breezeway, leaning on your cart, and trying to muster up the courage to walk inside.

And it’s easy to feel alone at work, too. Everyone else can pay attention to the corporate PowerPoint presentation in the conference room, but you’re sitting next to the closed door, thinking about how far you are from the office restroom, and flexing your leg muscles for a quick escape.

Every time we say “I am alone!” we are lying.

We are not alone in our struggles…and I made a video, just for you, to prove it:

4 Facts About Anxiety During Pregnancy & How to Find Help

Thursday, April 19th, 2012

4 Facts About Anxiety During Pregnancy & How to Find Help It’s common to have some concerns and worries about being pregnant, having a healthy child, giving birth, and parenting your little one, according to Pamela S. Wiegartz, Ph.D, and Kevin L. Gyoerkoe, PsyD, in their book, The Pregnancy & Postpartum Anxiety Workbook: Practical Skills to Help You Overcome Anxiety, Worry, Panic Attacks, Obsessions and Compulsions.

However, for some moms-to-be, anxiety becomes so severe and distressing that they’re unable to function day-to-day.

It’s only recently — over about the last decade — that researchers have begun exploring anxiety in pregnancy. Consequently, much more work is still needed.

But here’s what we do know.

OCD Is Most Often Treated with Antidepressants

Saturday, April 7th, 2012

OCD Is Most Often Treated with AntidepressantsIf you were ever wondering what was the most popular treatment for obsessive compulsive disorder (OCD), wonder no longer. It’s not psychotherapy. And it’s not some medication developed specifically for OCD.

Nope, it’s good ‘ole antidepressants.

Treatment options for obsessive compulsive disorder (OCD) are currently dominated by antidepressants, and this trend is expected to continue for the next seven to eight years.

That is, unless drugmakers step up their future research to develop new, more effective treatments, according to a new report by business intelligence company GlobalData.

Psych Central Week in Review #10: Anxiety, Antidepressants, and Learning

Sunday, April 1st, 2012

Students and life-long learners alike: at what time of day do you usually study?

When I was in college, I worked a few days per week as a campus computer lab monitor. (In other words, I got paid a few bucks to sit in a room with 30 computers and make sure that the printer didn’t jam up.)

I usually worked the closing (read: midnight) shift, and thanks to an incredibly competent cohort of classmates, I never had much work to do. If the printer jammed, the student who’d jammed the machine would usually walk right over, pull out the offending accordion-shaped piece of computer paper, and print their work again.

Call this job a study hall for the college set.

And study I did.

‘I Walked Away Really Confused,’ Says CBS’s Lesley Stahl on Antidepressants, Placebos

Monday, February 20th, 2012

I Walked Away Really Confused, Says CBSs Lesley Stahl on Antidepressants, PlacebosAre placebos — sugar pills — just as effective as antidepressant medications in the treatment of mild and moderate depression? That’s what a 60 Minutes piece last night tried to find out.

In discussing her reaction to discovering that the placebo effect may be more powerful than we previously knew in antidepressant research, CBS’s 60 Minutes correspondent Lesley Stahl says, “I walked away really confused.”

After viewing her piece, I walked away with the same reaction.

What’s an ordinary person supposed to gain from watching this segment, boiling down decades’ worth of antidepressant research and thousands of studies into less than 20 minutes? I’m not sure.

Poor Urban Depressed Patients Don’t Respond Well to Treatment

Thursday, December 22nd, 2011

Poor Urban Depressed Patients Don't Respond Well to TreatmentIn a small clinical study published a few weeks ago, researchers didn’t find much difference between the three treatment groups of depressed subjects they studied — a group that received antidepressant medications, a group that received a specific type of not-commonly-practiced psychodynamic psychotherapy, and a group that received a sugar pill.

But there were some serious issues with this study from the onset, issues that call into question not only the generalizability of the results, but also their validity. It’s a shame that Reuters, who picked up on the study just yesterday, glossed over the methodology problems of the study, and instead just repeated the results as a shiny new established fact.

And easily lost in the discussion is the best result of them all — 16 weeks was all that was needed for most people in the study (who completed it) to find improvement in the symptoms of their depression, no matter what the treatment.

Let’s see what went wrong, and what the study actually tells us…

Recent Comments
  • TellMeImWrong: Forgot to add, and don’t want any miscommunications. It’s not about who’s right or...
  • TellMeImWrong: Retreat to his “Cave”? Guess that means you’re subconsciously saying clubbing Women...
  • Maria: Part of the reason I love scary movies is because of the physical reactions I have to scenarios that are...
  • punkrockmom: What about the stay-at-home mom/wife?
  • J: I find this advice very good, but honestly, for someone who still struggles with depression despite lots of...
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