Have you told your doctor about the other medications or drugs you regularly take? If you’re on an antidepressant, you probably should.
If you’re taking non-steroidal anti-inflammatory drugs (NSAIDs), you may be less likely to experience the beneficial effects of the most commonly prescribed classes of antidepressants, SSRIs (such as Paxil, Zoloft and Prozac).
NSAIDs include ibuprofin (such as Advil, Motrin, and Midol), naproxen sodium (such as Aleve) and good ole aspirin.
According to an article appearing in the recently published The Carlat Psychiatry Report, that was the surprising conclusion of a paper published last year (Warnerschmidt Jl et al, Proc Natl Acad Sci USA 2011;108:9262–9267), and a newly released report reaches a similar conclusion.