How Does ECT Work in the Brain?
Electroconvulsive therapy (ECT) is an uncommon treatment for severe, chronic depression. It is used sparingly, partially because our understanding of why and how it works is still in the dark ages. It also doesn’t help that it can cause memory loss in many patients who undergo it (usually confined to just memory around ECT treatments, but occasionally also around older, longer-term memories as well), as well as increasing attention and concentration problems in a minority of people who try ECT.
However, a new study sheds light on the possible mechanism for how electroconvulsive therapy works, based upon one theory of how depression works in the brain.
The theory goes like this — depression isn’t caused by too little brain activity. It’s actually caused by too much brain activity, an overactive brain that has accidentally “hot-wired” multiple brain networks together. (How and why this hot-wiring occurs is still a mystery.)
So how can ECT undo this hot-wiring?


In 1920, behaviorist John Watson and his graduate student-turned-wife Rosalie Rayner conducted a conditioning experiment that everyone who’s ever taken an intro psychology course knows all too well: They taught 9-month-old Albert to fear a variety of stimuli that were seemingly innocuous to him from the start.
Last week, more than a few news agencies and blogs picked up the story that “one out of every 10 Wall Street employees is a psychopath.” This immediately caught my attention, because as a researcher, I found the statistic intriguing because it was so out of whack with the incidence of psychopathy in the general population. 
In
Although rare, school shootings like the one in Chardon, Ohio capture the horror imagination of every parent and teenager. And many people’s immediate reaction is, “Why would someone do that?”
Any father can learn to be a better dad. But it takes a commitment — and desire — to focus on one of the more important areas in your life. An involved dad is a better dad — one a child will appreciate not only as a kid, but in fond memories as they progress into adulthood. Children with involved fathers will grow up to be happier, better able to cope with life’s troubles, and healthier than children who have absent or uninvolved dads.
Are placebos — sugar pills — just as effective as antidepressant medications in the treatment of mild and moderate depression? That’s what a 60 Minutes piece last night tried to find out.
Writer Jennifer Yane once said, “I try to take one day at a time, but sometimes several days will attack me at once.” Admittedly, I spend too many days myself running from “the attacks of the calendars.” I am thinking that if I didn’t have so much stress in my life, I might be able to grab a cup of coffee first thing in the morning instead of jot down in my mood journal: how many hours I slept, where I am on my menstrual cycle, my anxiety/depression level upon waking, and any other important notes I need to record for my therapy and doctor’s visits.
I grew up in Batavia, N.Y., about ten miles down the road from the small town of LeRoy. I had just gone off to Cornell a few months before the big train derailment in December, 1970, that spilled cyanide crystals and about 30,000 gallons of the solvent called tricholoroethene onto the railroad bed.
A week ago, an op-ed appeared in the New York Times by L. Alan Sroufe, a professor emeritus of psychology at the University of Minnesota’s Institute of Child Development, questioning society’s reliance on medications to help children with attention deficit hyperactivity disorder (ADHD). He suggested that Ritalin has “gone wrong,” in that we simply rely too heavily on drugs to treat childhood disorders.
If you sprinkle a hefty dose of Catholic (or Jewish) guilt unto a fragile biochemistry headed toward a severe mood disorder, you usually arrive at some kind of a religious nut. Not that there’s anything wrong with that! For I am one.